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Keyword

MSH2

Description: A human gene encoding a DNA mismatch repair protein involved in genome maintenance and Lynch syndrome.
Wikidata ID: wiki/Q14911688
OpenAlex ID: keywords/msh2
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
1993 · Richard Fishel, Mary Kay Lescoe, et al. · Cell · 2,874
Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification
2002 · J. P. Schouten · Nucleic Acids Research · 2,700
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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
1998 · James G. Herman, Asad Umar, et al. · Proceedings of the National Academy of Sciences · 1,887
Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer
1994 · Nicholas C. Nicolaides, Nickolas Papadopoulos, et al. · Nature · 1,546
Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
2005 · Heather Hampel, Wendy L. Frankel, et al. · New England Journal of Medicine · 1,411
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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
2000 · Yi Wang, David Cortez, et al. · Genes & Development · 1,221
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Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease
1998 · Lauri A. Aaltonen, Reijo Salovaara, et al. · New England Journal of Medicine · 1,152
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A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting Highlights and Bethesda Guidelines
1997 · M. A. Rodriguez-Bigas, C. R. Boland, et al. · JNCI Journal of the National Cancer Institute · 1,137
Cancer Risks Associated With Germline Mutations in MLH1 , MSH2 , and MSH6 Genes in Lynch Syndrome
2011 · Valérie Bonadona · JAMA · 1,105
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair
1993 · Micheline Strand, Tomas A. Prolla, et al. · Nature · 1,077
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability.
1998 · J M Cunningham, E R Christensen, et al. · PubMed · 869
Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications
2009 · HT Lynch, PM Lynch, et al. · Clinical Genetics · 841
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over
1996 · Sean M. Baker, Annemieke W. Plug, et al. · Nature Genetics · 829
Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1
2008 · Marjolijn J L Ligtenberg, Roland P Kuiper, et al. · Nature Genetics · 819
Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors
2002 · Noralane M. Lindor, Lawrence J. Burgart, et al. · Journal of Clinical Oncology · 817
Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis
1996 · HF Vasen, JT Wijnen, et al. · Gastroenterology · 817
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Genetic susceptibility to non-polyposis colorectal cancer
1999 · Henry T Lynch, Albert de la Chapelle · Journal of Medical Genetics · 814
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
1995 · Niels de Wind, Marleen Dekker, et al. · Cell · 780
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Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts
2013 · Hans F A Vasen, Ignacio Blanco, et al. · Gut · 747
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Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression.
1997 · W Dietmaier, S Wallinger, et al. · PubMed · 743
Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer
1997 · P Peltomaki, HF Vasen · Gastroenterology · 738
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Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer
2016 · Rachel Pearlman, Wendy L. Frankel, et al. · JAMA Oncology · 709
Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer
2020 · Gaofeng Liang, Yanliang Zhu, et al. · Journal of Nanobiotechnology · 685
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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
2019 · Mev Dominguez-Valentin, Julian R. Sampson, et al. · Genetics in Medicine · 666
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Immunohistochemistry versus Microsatellite Instability Testing For Screening Colorectal Cancer Patients at Risk For Hereditary Nonpolyposis Colorectal Cancer Syndrome
2008 · Jinru Shia · Journal of Molecular Diagnostics · 643
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Works count: 8,524
Citation count: 230,800
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