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Keyword

MSH6

Description: MSH6 is a human gene encoding a DNA mismatch-repair protein involved in maintaining genomic stability and associated with hereditary cancer syndromes.
Wikidata ID: wiki/Q14911717
OpenAlex ID: keywords/msh6
Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
2005 · Heather Hampel, Wendy L. Frankel, et al. · New England Journal of Medicine · 1,411
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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
2000 · Yi Wang, David Cortez, et al. · Genes & Development · 1,221
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A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting Highlights and Bethesda Guidelines
1997 · M. A. Rodriguez-Bigas, C. R. Boland, et al. · JNCI Journal of the National Cancer Institute · 1,137
Cancer Risks Associated With Germline Mutations in MLH1 , MSH2 , and MSH6 Genes in Lynch Syndrome
2011 · Valérie Bonadona · JAMA · 1,105
Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
2011 · Tom Walsh, Silvia Casadei, et al. · Proceedings of the National Academy of Sciences · 933
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Genetic susceptibility to non-polyposis colorectal cancer
1999 · Henry T Lynch, Albert de la Chapelle · Journal of Medical Genetics · 814
Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts
2013 · Hans F A Vasen, Ignacio Blanco, et al. · Gut · 747
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Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
1997 · Michiko Miyaki, Motoko Konishi, et al. · Nature Genetics · 726
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer
2016 · Rachel Pearlman, Wendy L. Frankel, et al. · JAMA Oncology · 709
Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
2019 · Mev Dominguez-Valentin, Julian R. Sampson, et al. · Genetics in Medicine · 666
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Immunohistochemistry versus Microsatellite Instability Testing For Screening Colorectal Cancer Patients at Risk For Hereditary Nonpolyposis Colorectal Cancer Syndrome
2008 · Jinru Shia · Journal of Molecular Diagnostics · 643
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The crystal structure of DNA mismatch repair protein MutS binding to a G·T mismatch
2000 · Meindert H. Lamers, Anastassis Perrakis, et al. · Nature · 633
Screening for Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) among Endometrial Cancer Patients
2006 · Heather Hampel, Wendy Frankel, et al. · Cancer Research · 631
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Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer
2018 · Alicia Latham, Preethi Srinivasan, et al. · Journal of Clinical Oncology · 618
The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα
2013 · Feng Li, Guogen Mao, et al. · Cell · 593
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Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.
1996 · G T Marsischky, N Filosi, et al. · Genes & Development · 581
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Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
2017 · Pål Møller, Toni T Seppälä, et al. · Gut · 577
Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer
2016 · Nadine Tung, Nancy U. Lin, et al. · Journal of Clinical Oncology · 556
Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)
2007 · H F A Vasen, G Möslein, et al. · Journal of Medical Genetics · 554
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Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
2015 · Pål Møller, Toni Seppälä, et al. · Gut · 549
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Poly(ADP-ribose) Binds to Specific Domains in DNA Damage Checkpoint Proteins
2000 · Jutta M. Pleschke, Hanna E. Kleczkowska, et al. · Journal of Biological Chemistry · 541
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hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
1996 · Samir Acharya, Teresa Wilson, et al. · Proceedings of the National Academy of Sciences · 539
DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis
2002 · C Bernstein · Mutation Research/Reviews in Mutation Research · 527
Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer
2016 · Aung Ko Win, Mark A. Jenkins, et al. · Cancer Epidemiology Biomarkers & Prevention · 526
Mismatch Repair Deficiency, Microsatellite Instability, and Survival
2017 · Elizabeth C. Smyth, Andrew Wotherspoon, et al. · JAMA Oncology · 522
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Works count: 5,216
Citation count: 123,600
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