Keyword

mTHPC

Description: A chlorin-based photosensitizing drug, also called temoporfin, used in photodynamic therapy and studied for cellular uptake and photophysical effects.

Primary topic: Photodynamic Therapy Research Studies (84%)

OpenAlex ID: keywords/mthpc

Dye Sensitizers for Photodynamic Therapy

2013 · Alexandra Ormond, Harold Freeman · Materials · 846

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Temoporfin-loaded invasomes: Development, characterization and in vitro skin penetration studies

2008 · Nina Dragicevic-Curic, Dietrich Scheglmann, et al. · Journal of Controlled Release · 232

Photodynamic therapy with chlorins for diffuse malignant mesothelioma: initial clinical results

1991 · H-B Ris, HJ Altermatt, et al. · British Journal of Cancer · 217

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Interstitial photodynamic therapy as salvage treatment for recurrent head and neck cancer

2004 · P-J Lou, H R Jäger, et al. · British Journal of Cancer · 207

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mTHPC‐mediated photodynamic therapy for early oral squamous cell carcinoma

2004 · Colin Hopper, Alexander Kübler, et al. · International Journal of Cancer · 197

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mTHPC‐mediated photodynamic therapy in patients with advanced, incurable head and neck cancer: a multicenter study of 128 patients

2004 · Anil K. D'Cruz, Martin H. Robinson, et al. · Head & Neck · 181

Combining magnetic nanoparticles with cell derived microvesicles for drug loading and targeting

2015 · Amanda K.A. Silva, Nathalie Luciani, et al. · Nanomedicine Nanotechnology Biology and Medicine · 165

Insights into Photodynamic Therapy Dosimetry: Simultaneous Singlet Oxygen Luminescence and Photosensitizer Photobleaching Measurements

2012 · Mark T. Jarvi, Michael S. Patterson, et al. · Biophysical Journal · 154

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Surface charged temoporfin-loaded flexible vesicles: In vitro skin penetration studies and stability

2009 · Nina Dragicevic-Curic, Susanna Gräfe, et al. · International Journal of Pharmaceutics · 152

Comparative in vitro study on the characteristics of different photosensitizers employed in PDT

2010 · Juergen Berlanda, Tobias Kiesslich, et al. · Journal of Photochemistry and Photobiology B Biology · 149

Photophysical properties of 5,10,15,20-tetrakis(m-hydroxyphenyl)porphyrin (m-THPP), 5,10,15,20-tetrakis(m-hydroxyphenyl)chlorin (m-THPC) and 5,10,15,20-tetrakis(m-hydroxyphenyl)bacteriochlorin (m-THPBC): a comparative study

1999 · Raymond Bonnett, Paul Charlesworth, et al. · Journal of the Chemical Society Perkin Transactions 2 · 145

Development of different temoporfin-loaded invasomes—novel nanocarriers of temoporfin: Characterization, stability and in vitro skin penetration studies

2008 · Nina Dragicevic-Curic, Dietrich Scheglmann, et al. · Colloids and Surfaces B Biointerfaces · 144

Photodynamic therapy synergizes with PD-L1 checkpoint blockade for immunotherapy of CRC by multifunctional nanoparticles

2021 · Zeting Yuan, Guohua Fan, et al. · Molecular Therapy · 139

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Improved in vivo delivery of m-THPC via pegylated liposomes for use in photodynamic therapy

2011 · Melissa J. Bovis, Josephine H. Woodhams, et al. · Journal of Controlled Release · 134

Foscan® uptake and tissue distribution in relation to photodynamic efficacy

2003 · P Cramers, M Ruevekamp, et al. · British Journal of Cancer · 130

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Calculation of Singlet Oxygen Dose from Photosensitizer Fluorescence and Photobleaching During mTHPC Photodynamic Therapy of MLL Cells

2004 · Jonathan S. Dysart, Gurmit Singh, et al. · Photochemistry and Photobiology · 127

Photodynamic therapy using mTHPC for malignant disease in the oral cavity

1997 · Kathleen F.M. Fan, Colin Hopper, et al. · International Journal of Cancer · 125

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Meta-tetra(hydroxyphenyl)chlorin Photodynamic Therapy in Early-Stage Squamous Cell Carcinoma of the Head and Neck

2003 · Marcel P. Copper, I. Bing Tan, et al. · Archives of Otolaryngology - Head and Neck Surgery · 123

mTHPC – A drug on its way from second to third generation photosensitizer?

2011 · Mathias O. Senge · Photodiagnosis and Photodynamic Therapy · 122

Spectroscopic studies of photobleaching and photoproduct formation of meta(tetrahydroxyphenyl)chlorin (m-THPC) used in photodynamic therapy. The production of singlet oxygen by m-THPC

1998 · Christophe Hadjur, Norbert Lange, et al. · Journal of Photochemistry and Photobiology B Biology · 121

Indirect detection of photosensitizer ex vivo

2002 · Ludovic Bourré, Sonia Thibaut, et al. · Journal of Photochemistry and Photobiology B Biology · 118

Ultrafine Hydrogel Nanoparticles: Synthetic Approach and Therapeutic Application in Living Cells

2007 · De Gao, Hao Xu, et al. · Angewandte Chemie International Edition · 115

Lead structures for applications in photodynamic therapy. Part 1: Synthesis and variation of m-THPC (Temoporfin) related amphiphilic A2BC-type porphyrins

2005 · Arno Wiehe, Yasser M. Shaker, et al. · Tetrahedron · 109

Small Molecule-Initiated Light-Activated Semiconducting Polymer Dots: An Integrated Nanoplatform for Targeted Photodynamic Therapy and Imaging of Cancer Cells

2014 · Yanrong Zhang, Long Pang, et al. · Analytical Chemistry · 105

Apoptosis induced in vivo by photodynamic therapy in normal brain and intracranial tumour tissue

2000 · L Lilge, M Portnoy, et al. · British Journal of Cancer · 99

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Works count: 675

Citation count: 15,650