Keyword

NOD2

Description: NOD2 is a human protein-coding gene encoding an intracellular immune receptor that recognizes bacterial components and helps regulate inflammatory responses.

Primary topic: Immune Response and Inflammation (26%)

Wikidata ID: wiki/Q14912589

OpenAlex ID: keywords/nod2

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

2001 · Jean-Pierre Hugot, Mathias Chamaillard, et al. · Nature · 5,598

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

2001 · Yasunori Ogura, Denise K. Bonen, et al. · Nature · 5,032

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Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

2015 · Jimmy Z Liu, Suzanne van Sommeren, et al. · Nature Genetics · 2,601

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Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection

2003 · Stephen E. Girardin, Ivo G. Boneca, et al. · Journal of Biological Chemistry · 2,409

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A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

2006 · Jochen Hampe, Andre Franke, et al. · Nature Genetics · 1,898

Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract

2005 · Koichi S. Kobayashi, Mathias Chamaillard, et al. · Science · 1,776

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

2007 · John D Rioux, Ramnik J Xavier, et al. · Nature Genetics · 1,769

Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

2012 · Johanneke Kleinnijenhuis, Jessica Quintin, et al. · Proceedings of the National Academy of Sciences · 1,726

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Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2

2003 · Naohiro Inohara, Yasunori Ogura, et al. · Journal of Biological Chemistry · 1,696

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Nod2, a Nod1/Apaf-1 Family Member That Is Restricted to Monocytes and Activates NF-κB

2001 · Yasunori Ogura, Naohiro Inohara, et al. · Journal of Biological Chemistry · 1,362

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Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

2009 · Leonardo H Travassos, Leticia A M Carneiro, et al. · Nature Immunology · 1,306

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

2010 · Thomas B Clarke, Kimberly M Davis, et al. · Nature Medicine · 1,154

Diet Dominates Host Genotype in Shaping the Murine Gut Microbiota

2014 · Rachel N. Carmody, Georg K. Gerber, et al. · Cell Host & Microbe · 1,104

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Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

2001 · Jochen Hampe, Andrew Cuthbert, et al. · The Lancet · 1,092

Chronic inflammation: importance of NOD2 and NALP3 in interleukin-1β generation

2006 · L Ferrero-Miliani, O H Nielsen, et al. · Clinical & Experimental Immunology · 1,080

NODs: intracellular proteins involved in inflammation and apoptosis

2003 · Naohiro Inohara, Gabriel Nuñez · Nature reviews. Immunology · 1,064

Intracellular NOD-like Receptors in Host Defense and Disease

2007 · Thirumala-Devi Kanneganti, Mohamed Lamkanfi, et al. · Immunity · 1,061

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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

2009 · Rachel Cooney, John Baker, et al. · Nature Medicine · 1,048

Genomewide Association Study of Leprosy

2009 · Fu-Ren Zhang, Wei Huang, et al. · New England Journal of Medicine · 1,038

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CARD15/NOD2 Mutational Analysis and Genotype-Phenotype Correlation in 612 Patients with Inflammatory Bowel Disease

2002 · Suzanne Lesage, Habib Zouali, et al. · The American Journal of Human Genetics · 997

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NOD-LRR PROTEINS: Role in Host-Microbial Interactions and Inflammatory Disease

2005 · Naohiro Inohara, Mathias Chamaillard, et al. · Annual Review of Biochemistry · 992

CARD15 mutations in Blau syndrome

2001 · Corinne Miceli-Richard, Suzanne Lesage, et al. · Nature Genetics · 970

The NLR Gene Family: A Standard Nomenclature

2008 · Jenny P.-Y. Ting, Ruth C. Lovering, et al. · Immunity · 957

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The genetics and immunopathogenesis of inflammatory bowel disease

2008 · Judy H. Cho · Nature reviews. Immunology · 938

Function of Nod‐like receptors in microbial recognition and host defense

2008 · Luigi Franchi, Neil Warner, et al. · Immunological Reviews · 903

Works count: 6,275

Citation count: 207,600