Keyword

open probability

Description: The probability that an ion channel is in its conducting state at a given time, a measure used in electrophysiology and channel biophysics.

Primary topic: Ion channel regulation and function (64%)

OpenAlex ID: keywords/open-probability

PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor)

2000 · Steven O Marx, Steven Reiken, et al. · Cell · 1,980

PDF

Bell-shaped calcium-response curves of lns(l,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

1991 · llya Bezprozvanny, James Watras, et al. · Nature · 1,713

Stretch‐activated single ion channel currents in tissue‐cultured embryonic chick skeletal muscle.

1984 · F Guharay, F Sachs · The Journal of Physiology · 995

Voltage Sensor of Kv1.2: Structural Basis of Electromechanical Coupling

2005 · Stephen B. Long, Ernest B. Campbell, et al. · Science · 979

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

1994 · Anne-Marie B. Brillantes, Karol Ondrias, et al. · Cell · 828

The variance of sodium current fluctuations at the node of Ranvier

1980 · F. J. Sigworth · The Journal of Physiology · 775

Activating Mutations in theABCC8Gene in Neonatal Diabetes Mellitus

2006 · Andrey P. Babenko, Michel Polak, et al. · New England Journal of Medicine · 660

PDF

Blocking and isolation of a calcium channel from neurons in mammals and cephalopods utilizing a toxin fraction (FTX) from funnel-web spider poison.

1989 · R Llinás, M Sugimori, et al. · Proceedings of the National Academy of Sciences · 631

Ca 2+ /Calmodulin-Dependent Protein Kinase II Phosphorylation Regulates the Cardiac Ryanodine Receptor

2004 · Xander H.T. Wehrens, Stephan E. Lehnart, et al. · Circulation Research · 623

Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder

2005 · Wei Du, Jocelyn F Bautista, et al. · Nature Genetics · 576

Ryanodine modifies conductance and gating behavior of single Ca2+ release channel

1987 · E. Rousseau, J. S. Smith, et al. · American Journal of Physiology-Cell Physiology · 551

Inactivation of NMDA Receptors by Direct Interaction of Calmodulin with the NR1 Subunit

1996 · Michael D Ehlers, Su Zhang, et al. · Cell · 541

PDF

Sulfonylurea Stimulation of Insulin Secretion

2002 · Peter Proks, Frank Reimann, et al. · Diabetes · 511

PDF

Coupling between Voltage Sensor Activation, Ca2+ Binding and Channel Opening in Large Conductance (BK) Potassium Channels

2002 · Frank T. Horrigan, Richard W. Aldrich · The Journal of General Physiology · 498

Activation of KATP channels by H2S in rat insulin‐secreting cells and the underlying mechanisms

2005 · Wei Yang, Guangdong Yang, et al. · The Journal of Physiology · 469

The G Protein–Gated Potassium Current I K,ACh Is Constitutively Active in Patients With Chronic Atrial Fibrillation

2005 · D. Dobrev, A. Friedrich, et al. · Circulation · 463

The Role of Calsequestrin, Triadin, and Junctin in Conferring Cardiac Ryanodine Receptor Responsiveness to Luminal Calcium

2004 · Inna Györke, Nichole Hester, et al. · Biophysical Journal · 442

PDF

Gating and regulation of connexin 43 (Cx43) hemichannels

2003 · Jorge E. Contreras, Juan C. Sáez, et al. · Proceedings of the National Academy of Sciences · 437

Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

1984 · Michimasa Soejima, Akinori Noma · Pflügers Archiv - European Journal of Physiology · 435

Subunit‐specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles

2005 · Kevin Erreger, Shashank M. Dravid, et al. · The Journal of Physiology · 427

Potentiation of NMDA receptor currents by arachidonic acid

1992 · Barbara Miller, Monique Sarantis, et al. · Nature · 426

Ivacaftor potentiation of multiple CFTR channels with gating mutations

2012 · Haihui Yu, Bill Burton, et al. · Journal of Cystic Fibrosis · 423

PDF

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

1996 · Dmitri Firsov, Laurent Schild, et al. · Proceedings of the National Academy of Sciences · 421

Single channel recordings of Ca2+-activated K+ currents in rat muscle cell culture

1981 · Barry S. Pallotta, Karl L. Magleby, et al. · Nature · 414

Connexin-based gap junction hemichannels: Gating mechanisms

2005 · Juan C. Sáez, Mauricio A. Retamal, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 411

PDF

Works count: 4,057

Citation count: 165,100