Keyword

osteoclastogenesis

Description: The biological process by which osteoclasts form and mature, studied in bone remodeling and disorders such as arthritis and osteoporosis.

Primary topic: Bone Metabolism and Diseases (61%)

Related topic: Bone Metabolism and Diseases (61%)

OpenAlex ID: keywords/osteoclastogenesis

Osteoclast differentiation and activation

2003 · William J. Boyle, W. Scott Simonet, et al. · Nature · 6,636

Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

1998 · D.L Lacey, E Timms, et al. · Cell · 5,439

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Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

1997 · W.S Simonet, D.L Lacey, et al. · Cell · 5,128

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1998 · Hisataka Yasuda, Nobuyuki Shima, et al. · Proceedings of the National Academy of Sciences · 4,228

Bone Resorption by Osteoclasts

2000 · Steven L. Teitelbaum · Science · 3,958

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1999 · Young-Yun Kong, Hiroki Yoshida, et al. · Nature · 3,350

Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

2002 · Hiroshi Takayanagi, Sunhwa Kim, et al. · Developmental Cell · 2,690

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Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis

2000 · Stavros C. Manolagas · Endocrine Reviews · 2,568

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

1998 · N. Bucay, I. Sarosi, et al. · Genes & Development · 2,485

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Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families

1999 · Tatsuo Suda, Naoyuki Takahashi, et al. · Endocrine Reviews · 2,336

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

1999 · Young-Yun Kong, Ulrich Feige, et al. · Nature · 1,857

Functions of RANKL/RANK/OPG in bone modeling and remodeling

2008 · Brendan F. Boyce, Lianping Xing · Archives of Biochemistry and Biophysics · 1,837

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

2011 · Tomoki Nakashima, Mikihito Hayashi, et al. · Nature Medicine · 1,770

Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone.

1998 · R S Weinstein, R L Jilka, et al. · Journal of Clinical Investigation · 1,754

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Genetic regulation of osteoclast development and function

2003 · Steven L. Teitelbaum, F. Patrick Ross · Nature Reviews Genetics · 1,701

IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

1999 · Shigeru Kotake, Nobuyuki Udagawa, et al. · Journal of Clinical Investigation · 1,696

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Bone Marrow, Cytokines, and Bone Remodeling — Emerging Insights into the Pathophysiology of Osteoporosis

1995 · Stavros C. Manolagas, Robert L. Jilka · New England Journal of Medicine · 1,668

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

1999 · Hailing Hsu, David L. Lacey, et al. · Proceedings of the National Academy of Sciences · 1,638

Canonical Wnt Signaling in Differentiated Osteoblasts Controls Osteoclast Differentiation

2005 · Donald A. Glass, Peter Bialek, et al. · Developmental Cell · 1,558

Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

2006 · Kojiro Sato, Ayako Suematsu, et al. · The Journal of Experimental Medicine · 1,551

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Minireview: The OPG/RANKL/RANK System

2001 · S. Khosla · Endocrinology · 1,512

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RANK is essential for osteoclast and lymph node development

1999 · W. C. Dougall, M. Glaccum, et al. · Genes & Development · 1,478

Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

1992 · Robert L. Jilka, Giao Hangoc, et al. · Science · 1,442

TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

2000 · Jonathan Lam, Sunao Takeshita, et al. · Journal of Clinical Investigation · 1,436

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The molecular understanding of osteoclast differentiation

2006 · Masataka Asagiri, Hiroshi Takayanagi · Bone · 1,361

Works count: 29,900

Citation count: 860,100