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Keyword

p50 subunit

Description: The p50 protein component of NF-κB, a transcription-factor subunit that binds DNA alone or with other NF-κB proteins.
OpenAlex ID: keywords/p50-subunit
Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses
1995 · William C Sha, Hsiou-Chi Liou, et al. · Cell · 1,157
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Requirement for NF-κB in osteoclast and B-cell development
1997 · Guido Franzoso, Louise Carlson, et al. · Genes & Development · 995
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The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product
1990 · Mark Kieran, Volker Blank, et al. · Cell · 875
Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal
1990 · Sankar Ghosh, Ann M. Gifford, et al. · Cell · 853
Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62
1992 · James R. Matthews, Naomi Wakasugi, et al. · Nucleic Acids Research · 831
The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B.
1991 · M.L. Schmitz, P.A. Baeuerle · The EMBO Journal · 796
I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention.
1992 · A A Beg, S M Ruben, et al. · Genes & Development · 718
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Structure of the NF-κB p50 homodimer bound to DNA
1995 · Christoph W. Müller, Félix A. Rey, et al. · Nature · 535
A critical role for NF-κB in Gata3 expression and TH2 differentiation in allergic airway inflammation
2001 · Jyoti Das, Chang-Hung Chen, et al. · Nature Immunology · 520
Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ
2004 · Masahiro Yamamoto, Soh Yamazaki, et al. · Nature · 496
Inhibition of NF- B DNA Binding by Nitric Oxide
1996 · J. R. Matthews, C. H. Botting, et al. · Nucleic Acids Research · 495
NF-κB Activation: The IκB Kinase Revealed?
1997 · Ilana Stancovski, David Baltimore · Cell · 492
Selection of Optimal κB/Rel DNA-Binding Motifs: Interaction of Both Subunits of NF-κB with DNA Is Required for Transcriptional Activation
1992 · Charles Kunsch, Steven M. Ruben, et al. · Molecular and Cellular Biology · 491
Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice.
1995 · A A Beg, W C Sha, et al. · Genes & Development · 473
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Inducible Nuclear Expression of Newly Synthesized IκBα Negatively Regulates DNA-Binding and Transcriptional Activities of NF-κB
1995 · Fernando Arenzana-Seisdedos, Jill Thompson, et al. · Molecular and Cellular Biology · 433
Constitutive NF-kB Activity in Neurons
1994 · Christian Kaltschmidt, Barbara Kaltschmidt, et al. · Molecular and Cellular Biology · 398
NF-κB signaling in cerebral ischemia
2008 · D.A. Ridder, M. Schwaninger · Neuroscience · 386
NF-κB dysregulation in microRNA-146a–deficient mice drives the development of myeloid malignancies
2011 · Jimmy L. Zhao, Dinesh S. Rao, et al. · Proceedings of the National Academy of Sciences · 385
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Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-κB subunit
1992 · Thomas Henkel, Ulrike Zabel, et al. · Cell · 385
Inhibition of NF-κB by S-Nitrosylation
2001 · Harvey E. Marshall, Jonathan S. Stamler · Biochemistry · 379
Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B.
1992 · T Fujita, G P Nolan, et al. · Genes & Development · 369
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The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms.
1993 · M L Scott, T Fujita, et al. · Genes & Development · 354
The candidate oncoprotein Bcl-3 is an antagonist of pSO/NF-κB-mediated inhibition
1992 · Guido Franzoso, Vincent Bours, et al. · Nature · 320
NF-κB Subunit Regulation in Nontransformed CD4 + T Lymphocytes
1992 · Sang-Mo Kang, Annie-Chen Tran, et al. · Science · 314
Acetylation of Poly(ADP-ribose) Polymerase-1 by p300/CREB-binding Protein Regulates Coactivation of NF-κB-dependent Transcription
2005 · Paul O. Hassa, Sandra S. Haenni, et al. · Journal of Biological Chemistry · 306
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Works count: 620
Citation count: 37,960
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