Keyword

PDE1

Description: A cyclic nucleotide phosphodiesterase enzyme that hydrolyzes cAMP and cGMP and participates in intracellular signaling.

Primary topic: Phosphodiesterase function and regulation (64%)

Wikidata ID: wiki/Q5864323

OpenAlex ID: keywords/pde1

Novel sensing mechanisms and targets for the cAMP–protein kinase A pathway in the yeast Saccharomyces cerevisiae

1999 · Johan M. Thevelein, Johannes H. De Winde · Molecular Microbiology · 677

Poly(ADP-ribose) (PAR) polymer is a death signal

2006 · Shaida A. Andrabi, No Soo Kim, et al. · Proceedings of the National Academy of Sciences · 643

Farnesol and dodecanol effects on the Candida albicans Ras1‐cAMP signalling pathway and the regulation of morphogenesis

2007 · Amber Davis‐Hanna, Amy E. Piispanen, et al. · Molecular Microbiology · 250

Antihyperglycemic and blood pressure-reducing effects of stevioside in the diabetic Goto-Kakizaki rat

2003 · P.B. Jeppesen, S. Gregersen, et al. · Metabolism · 239

Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae.

1987 · J Nikawa, P Sass, et al. · Molecular and Cellular Biology · 219

Characterization and Functional Relevance of Cyclic Nucleotide Phosphodiesterase Isoenzymes of the Human Prostate

2001 · STEFAN ÜCKERT, ANDREA KÜTHE, et al. · The Journal of Urology · 192

The PDE1 -encoded Low-Affinity Phosphodiesterase in the Yeast Saccharomyces cerevisiae Has a Specific Function in Controlling Agonist-induced cAMP Signaling

1999 · Pingsheng Ma, Stefaan Wera, et al. · Molecular Biology of the Cell · 191

Molecular cloning of rat homologues of the Drosophila melanogaster dunce cAMP phosphodiesterase: evidence for a family of genes.

1989 · J V Swinnen, D R Joseph, et al. · Proceedings of the National Academy of Sciences · 172

Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways

2016 · Wei-Chien Hung, Jessica R. Yang, et al. · Cell Reports · 165

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Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure–activity relationships

2004 · Wun-Chang Ko, Chwen-Ming Shih, et al. · Biochemical Pharmacology · 164

Two DHH Subfamily 1 Proteins in Streptococcus pneumoniae Possess Cyclic Di-AMP Phosphodiesterase Activity and Affect Bacterial Growth and Virulence

2013 · Yinlan Bai, Jun Yang, et al. · Journal of Bacteriology · 161

Characterization of a fission yeast gene, gpa2, that encodes a G alpha subunit involved in the monitoring of nutrition.

1992 · T Isshiki, N Mochizuki, et al. · Genes & Development · 157

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Phosphodiesterase regulation of nitric oxide signaling

2007 · D KASS, E TAKIMOTO, et al. · Cardiovascular Research · 156

Phosphodiesterase 1 Upregulation in Pulmonary Arterial Hypertension

2007 · Ralph Theo Schermuly, Soni Savai Pullamsetti, et al. · Circulation · 151

Identification of Pathogenicity Mutants of the Rice Blast Fungus Magnaporthe grisea by Insertional Mutagenesis

1999 · Pascale V. Balhadère, Andrew J. Foster, et al. · Molecular Plant-Microbe Interactions · 149

Phosphodiesterase Isoforms in the Pulmonary Arterial Circulation of the Rat: Changes in Pulmonary Hypertension

1997 · M.R. Maclean, E.D. Johnston, et al. · Journal of Pharmacology and Experimental Therapeutics · 144

Ca2+-calmodulin-dependent phosphodiesterase (PDE1): Current perspectives

2005 · Tasmina A. Goraya, Dermot M.F. Cooper · Cellular Signalling · 140

Calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1)

1999 · R. Kakkar, R. V. S. Raju, et al. · Cellular and Molecular Life Sciences · 136

Selective Cyclic Nucleotide Phosphodiesterase Inhibitors as Potential Therapeutic Agents

1977 · B Weiss, W N Hait · The Annual Review of Pharmacology and Toxicology · 131

Reduction in the intracellular cAMP level triggers initiation of sexual development in fission yeast

1992 · Nobuyoshi Mochizuki, Masayuki Yamamoto · Molecular and General Genetics MGG · 128

Compound- and enzyme-specific phosphodiester hydrolysis mechanisms revealed by δ18O of dissolved inorganic phosphate: Implications for marine P cycling

2009 · Yuhong Liang, Ruth E. Blake · Geochimica et Cosmochimica Acta · 119

TRI6 and TRI10 play different roles in the regulation of deoxynivalenol (DON) production by cAMP signalling in Fusarium graminearum

2016 · Cong Jiang, Chengkang Zhang, et al. · Environmental Microbiology · 116

Isoforms of Cyclic Nucleotide Phosphodiesterase PDE3 and Their Contribution to cAMP Hydrolytic Activity in Subcellular Fractions of Human Myocardium

2005 · Ryan Hambleton, Judith Krall, et al. · Journal of Biological Chemistry · 114

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Multiple roles and diverse regulation of the Ras/cAMP/protein kinase A pathway in Candida albicans

2018 · Guanghua Huang, Qian Huang, et al. · Molecular Microbiology · 113

Differential CNS expression of alternative mRNA isoforms of the mammalian genes encoding cAMP-specific phosphodiesterases

1994 · Graeme B. Bolger, Linda Rodgers, et al. · Gene · 110

Works count: 412

Citation count: 11,280