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Keyword

pederin

Description: A potent bioactive polyketide compound produced by symbiotic bacteria associated with Paederus beetles, studied for its toxicity and antitumor activity.
Wikidata ID: wiki/Q8214251
OpenAlex ID: keywords/pederin
A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
2002 · Jörn Piel · Proceedings of the National Academy of Sciences · 609
Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
2004 · Jörn Piel, Dequan Hui, et al. · Proceedings of the National Academy of Sciences · 543
Paederus, Sensu Lato (Coleoptera: Staphylinidae): Natural History and Medical Importance1
1987 · J.H. Frank, K. Kanamitsu · Journal of Medical Entomology · 176
Exploring the Chemistry of Uncultivated Bacterial Symbionts: Antitumor Polyketides of the Pederin Family
2005 · Jörn Piel, Daniel Butzke, et al. · Journal of Natural Products · 163
Molecular identification of an endosymbiotic bacterium associated with pederin biosynthesis in Paederus sabaeus (Coleoptera: Staphylinidae)
2002 · Rupert L.L. Kellner · Insect Biochemistry and Molecular Biology · 160
Differential efficacy of toxic pederin in deterring potential arthropod predators of Paederus (Coleoptera: Staphylinidae) offspring
1996 · Rupert L. L. Kellner, Konrat Dettner · Oecologia · 153
Antiviral and antitumor agents from a New Zealand sponge, Mycale sp. 2. Structures and solution conformations of mycalamides A and B
1990 · Nigel B. Perry, John W. Blunt, et al. · The Journal of Organic Chemistry · 151
Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses
2013 · Annette Kampa, Andrey N. Gagunashvili, et al. · Proceedings of the National Academy of Sciences · 147
Bacterial Symbionts: Prospects for the Sustainable Production of Invertebrate-Derived Pharmaceuticals
2005 · J. Piel · Current Medicinal Chemistry · 147
Evidence for a Symbiosis Island Involved in Horizontal Acquisition of Pederin Biosynthetic Capabilities by the Bacterial Symbiont of Paederus fuscipes Beetles
2004 · Jörn Piel, Ivonne Höfer, et al. · Journal of Bacteriology · 134
Targeting modular polyketide synthases with iteratively acting acyltransferases from metagenomes of uncultured bacterial consortia
2004 · Jörn Piel, Dequan Hui, et al. · Environmental Microbiology · 127
Unprecedented Diversity of Catalytic Domains in the First Four Modules of the Putative Pederin Polyketide Synthase
2003 · Jörn Piel, Gaiping Wen, et al. · ChemBioChem · 114
Paederus dermatitis in northern Iran: a report of 156 cases
2003 · Omid Zargari, Arash Kimyai‐Asadi, et al. · International Journal of Dermatology · 105
An outbreak of Paederus dermatitis in a suburban hospital in South India: A report of 123 cases and review of literature
2007 · Pushpa Gnanaraj, V. Venugopal, et al. · Journal of the American Academy of Dermatology · 103
Total Synthesis and Biological Evaluation of Pederin, Psymberin, and Highly Potent Analogs
2011 · Shuangyi Wan, Fanghui Wu, et al. · Journal of the American Chemical Society · 89
An Enzymatic Domain for the Formation of Cyclic Ethers in Complex Polyketides
2013 · Petra Pöplau, Sarah Frank, et al. · Angewandte Chemie International Edition · 83
Studies toward the Unique Pederin Family Member Psymberin: Full Structure Elucidation, Two Alternative Total Syntheses, and Analogs
2012 · Yu Feng, Xin Jiang, et al. · Journal of the American Chemical Society · 83
The structure of Pederin.
1965 · C. Cardani, D. Ghiringhelli, et al. · Tetrahedron Letters · 81
13-Deoxytedanolide, a marine sponge-derived antitumor macrolide, binds to the 60S large ribosomal subunit
2004 · Shinichi Nishimura, Shigeki Matsunaga, et al. · Bioorganic & Medicinal Chemistry · 78
Isolation, biological activity, synthesis, and medicinal chemistry of the pederin/mycalamide family of natural products
2012 · R. Adam Mosey, Paul E. Floreancig · Natural Product Reports · 77
Total Synthesis of Pederin
2007 · John C. Jewett, Viresh H. Rawal · Angewandte Chemie International Edition · 76
Oedemerid blister beetle dermatosis: A review
1990 · D.S.H. Nicholls, T.I. Christmas, et al. · Journal of the American Academy of Dermatology · 74
Suppression of pederin biosynthesis through antibiotic elimination of endosymbionts in Paederus sabaeus
2001 · Rupert L.L. Kellner · Journal of Insect Physiology · 73
Synthesis of Psymberin Analogues: Probing a Functional Correlation with the Pederin/Mycalamide Family of Natural Products
2006 · Xin Jiang, Noelle Williams, et al. · Organic Letters · 71
The crystal and molecular structure of pederin di-p-bromobenzoate
1968 · Akio Furusaki, Tokunosuké Watanabé, et al. · Tetrahedron Letters · 71
Works count: 227
Citation count: 6,059
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