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Keyword

penems

Description: Penems are a class of beta-lactam antibiotics characterized by a fused ring structure and used to inhibit bacterial cell-wall synthesis.
Wikidata ID: wiki/Q7162597
OpenAlex ID: keywords/penems
β-lactam antibiotics: An overview from a medicinal chemistry perspective
2020 · Lidia Moreira Lima, Bianca Nascimento Monteiro da Silva, et al. · European Journal of Medicinal Chemistry · 648
Crystal structure of a bacterial signal peptidase in complex with a β-lactam inhibitor
1998 · Mark Paetzel, Ross E. Dalbey, et al. · Nature · 305
Recent Developments in the Field of β‐Lactam Antibiotics
1985 · Walter Dürckheimer, Jürgen Blumbach, et al. · Angewandte Chemie International Edition in English · 302
Killing and regrowth of bacteria in vitro: a review.
1990 · W A Craig, S C Ebert · PubMed · 301
Outer membrane protein D2 catalyzes facilitated diffusion of carbapenems and penems through the outer membrane of Pseudomonas aeruginosa
1990 · J Trias, H Nikaido · Antimicrobial Agents and Chemotherapy · 291
Recent progress in the chemical synthesis of antibiotics
1991 · European Journal of Medicinal Chemistry · 246
Type I -Lactamases of Gram-Negative Bacteria: Interactions with -Lactam Antibiotics
1986 · C. C. Sanders, W. E. SandersJr · The Journal of Infectious Diseases · 167
The penems, a new class of .beta.-lactam antibiotics: 6-acylaminopenem-3-carboxylic acids
1978 · I. Ernest, J. Gosteli, et al. · Journal of the American Chemical Society · 157
Current Challenges in Antimicrobial Chemotherapy
2010 · Carine Bebrone, Patricia Lassaux, et al. · Drugs · 154
Nephrotoxicity of beta-lactam antibiotics: mechanisms and strategies for prevention
1997 · Bruce M. Tune · Pediatric Nephrology · 143
The Mechanisms of Reactions of β-Lactam Antibiotics
1987 · Michael I. Page · Advances in physical organic chemistry · 126
Characterization of Purified New Delhi Metallo-β-lactamase-1
2011 · Pei W. Thomas, Min Zheng, et al. · Biochemistry · 122
Discovery and development of new antimicrobial agents
1990 · T D Gootz · Clinical Microbiology Reviews · 110
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In vitro evaluation of BRL 42715, a novel beta-lactamase inhibitor
1989 · K Coleman, D R Griffin, et al. · Antimicrobial Agents and Chemotherapy · 96
Synthesis and in vitro activity of a new carbapenem, RS-533.
1983 · TETSUO MIYADERA, YUKIO SUGIMURA, et al. · The Journal of Antibiotics · 92
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Redefining penems
2006 · Axel Dalhoff, Nebojsa Janjic, et al. · Biochemical Pharmacology · 85
Beta-lactams and their potential use as novel anticancer chemotherapeutics drugs
2004 · Deborah Kuhn · Frontiers in bioscience · 74
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A new synthesis of penems, the oxalimide cyclization reaction
1982 · Adriano Afonso, Frank Hon, et al. · Journal of the American Chemical Society · 73
The impact of beta-lactamases on the development of novel antimicrobial agents.
2002 · Karen Bush · PubMed · 71
Beta-lactamase inhibitors: agents to overcome bacterial resistance.
1998 · S N Maiti, O A Phillips, et al. · PubMed · 69
A γ-lactam analogue of penems possessing antibacterial activity
1986 · Jack E Baldwin, Christopher Lowe, et al. · Tetrahedron Letters · 69
Survey of in vitro susceptibilities of Vibrio cholerae O1 and O139 to antimicrobial agents
1995 · T Yamamoto, G B Nair, et al. · Antimicrobial Agents and Chemotherapy · 68
β-Lactamase Inhibitors: Agents to Overcome Bacterial Resistance
1998 · Samarendra N. Maiti, Oludotun A. Phillips, et al. · Current Medicinal Chemistry · 67
The penems, a new class of .beta.-lactam antibiotics. 2. Total synthesis of racemic 6-unsubstituted representatives
1979 · M. Lang, K. Prasad, et al. · Journal of the American Chemical Society · 67
The penems, a new class of .beta.-lactam antibiotics. 5. Total synthesis of racemic 6-.alpha.-hydroxyethylpenemcarboxylic acids
1980 · H. R. Pfaendler, J. Gosteli, et al. · Journal of the American Chemical Society · 66
Works count: 356
Citation count: 6,885
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