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Keyword

PKD2

Description: A human protein-coding gene that encodes polycystin-2 and is associated with autosomal dominant polycystic kidney disease.
Wikidata ID: wiki/Q18030564
OpenAlex ID: keywords/pkd2
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
2003 · Surya M. Nauli, Francis J. Alenghat, et al. · Nature Genetics · 2,062
PKD2 , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein
1996 · Toshio Mochizuki, Guanqing Wu, et al. · Science · 1,406
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
2000 · Kazushige Hanaoka, Feng Qian, et al. · Nature · 819
Polycystic Kidney Disease
2008 · Peter C. Harris, Vicente E. Torres · Annual Review of Medicine · 815
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
2015 · Benjamin S. Freedman, Craig R. Brooks, et al. · Nature Communications · 781
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Unified Criteria for Ultrasonographic Diagnosis of ADPKD
2008 · York Pei, James Obaji, et al. · Journal of the American Society of Nephrology · 764
PKD1 interacts with PKD2 through a probable coiled-coil domain
1997 · Feng Qian, F. Joseph Germino, et al. · Nature Genetics · 662
Comparison of phenotypes of polycystic kidney disease types 1 and 2
1999 · Nick Hateboer, Marjan A v Dijk, et al. · The Lancet · 628
Genetics and Pathogenesis of Polycystic Kidney Disease
2002 · Peter Igarashi, Stefan Somlo · Journal of the American Society of Nephrology · 594
Somatic Inactivation of Pkd2 Results in Polycystic Kidney Disease
1998 · Guanqing Wu, Vivette D'Agati, et al. · Cell · 570
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A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
1999 · Maureen M. Barr, Paul W. Sternberg · Nature · 541
Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease
2002 · Gregory J. Pazour, Jovenal T. San Agustin, et al. · Current Biology · 531
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A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney
2004 · Zhaoxia Sun, Adam Amsterdam, et al. · Development · 528
Homo- and heterodimeric interactions between the gene products of PKD1 and PKD 2
1997 · Leonidas Tsiokas, Emily Kim, et al. · Proceedings of the National Academy of Sciences · 477
Mutations in GANAB , Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease
2016 · Binu Porath, Vladimir G. Gainullin, et al. · The American Journal of Human Genetics · 474
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PKD1 Induces p21waf1 and Regulation of the Cell Cycle via Direct Activation of the JAK-STAT Signaling Pathway in a Process Requiring PKD2
2002 · Anil Kumar Bhunia, Klaus Piontek, et al. · Cell · 454
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Comprehensive Molecular Diagnostics in Autosomal Dominant Polycystic Kidney Disease
2007 · Sandro Rossetti, Mark B. Consugar, et al. · Journal of the American Society of Nephrology · 440
The Ion Channel Polycystin-2 Is Required for Left-Right Axis Determination in Mice
2002 · Petra Pennekamp, Christina Karcher, et al. · Current Biology · 425
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Genetic Complexity of Autosomal Dominant Polycystic Kidney and Liver Diseases
2017 · Emilie Cornec-Le Gall, Vicente E. Torres, et al. · Journal of the American Society of Nephrology · 409
Cardiac defects and renal failure in mice with targeted mutations in Pkd2
2000 · Guanqing Wu, Glen S. Markowitz, et al. · Nature Genetics · 399
Identification of a missense mutation in the bovine ABCG2 gene with a major effect on the QTL on chromosome 6 affecting milk yield and composition in Holstein cattle
2005 · Miri Cohen-Zinder, Eyal Seroussi, et al. · Genome Research · 377
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Polycystin-1 and -2 Dosage Regulates Pressure Sensing
2009 · Reza Sharif-Naeini, Joost H.A. Folgering, et al. · Cell · 345
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A transcriptional network in polycystic kidney disease
2004 · Lionel Gresh, Evelyne Fischer, et al. · The EMBO Journal · 335
Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIβ at the Golgi complex
2005 · Angelika Hausser, Peter Storz, et al. · Nature Cell Biology · 333
Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades
2009 · Wissam A. AbouAlaiwi, Maki Takahashi, et al. · Circulation Research · 327
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Works count: 2,077
Citation count: 55,890
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