Keyword

population stratification

Description: Population stratification is genetic variation among subpopulations, often reflected in differing allele frequencies, that can confound genetic association studies.

Primary topic: Genetic Associations and Epidemiology (42%)

Wikidata ID: wiki/Q7229824

OpenAlex ID: keywords/population-stratification

PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses

2007 · Shaun Purcell, Benjamin Neale, et al. · The American Journal of Human Genetics · 33,996

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Principal components analysis corrects for stratification in genome-wide association studies

2006 · Alkes L Price, Nick J Patterson, et al. · Nature Genetics · 10,212

Fast model-based estimation of ancestry in unrelated individuals

2009 · David H. Alexander, John Novembre, et al. · Genome Research · 9,838

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

2007 · Paul R. Burton, David G. Clayton, et al. · Nature · 9,444

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LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

2015 · Brendan K Bulik-Sullivan, Po-Ru Loh, et al. · Nature Genetics · 5,534

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Genome-wide efficient mixed-model analysis for association studies

2012 · Xiang Zhou, Matthew Stephens · Nature Genetics · 3,606

Robust relationship inference in genome-wide association studies

2010 · Ani Manichaikul, Josyf C. Mychaleckyj, et al. · Bioinformatics · 3,516

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Genetic Structure of Human Populations

2002 · Noah A. Rosenberg, Jonathan K. Pritchard, et al. · Science · 2,996

Variance component model to account for sample structure in genome-wide association studies

2010 · Hyun Min Kang, Jae Hoon Sul, et al. · Nature Genetics · 2,806

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An integrated map of structural variation in 2,504 human genomes

2015 · Peter H. Sudmant, Tobias Rausch, et al. · Nature · 2,350

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The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

2000 · David Altshuler, Joel N. Hirschhorn, et al. · Nature Genetics · 1,768

The Missing Diversity in Human Genetic Studies

2019 · Giorgio Sirugo, Scott M. Williams, et al. · Cell · 1,501

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A Note on Exact Tests of Hardy-Weinberg Equilibrium

2005 · Janis E. Wigginton, David J. Cutler, et al. · The American Journal of Human Genetics · 1,447

Accounting for Decay of Linkage Disequilibrium in Haplotype Inference and Missing-Data Imputation

2005 · Matthew Stephens, Paul Scheet · The American Journal of Human Genetics · 1,349

New approaches to population stratification in genome-wide association studies

2010 · Alkes L. Price, Noah A. Zaitlen, et al. · Nature Reviews Genetics · 1,206

Population stratification and spurious allelic association

2003 · Lon R Cardon, Lyle J Palmer · The Lancet · 1,205

Use of Unlinked Genetic Markers to Detect Population Stratification in Association Studies

1999 · Jonathan K. Pritchard, Noah A. Rosenberg · The American Journal of Human Genetics · 1,197

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Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking

1996 · Jonathan Benjamin, Lin Li, et al. · Nature Genetics · 1,194

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Enterotypes in the landscape of gut microbial community composition

2017 · Paul I. Costea, Falk Hildebrand, et al. · Nature Microbiology · 1,135

Pedigree disequilibrium tests for multilocus haplotypes

2003 · Frank Dudbridge · Genetic Epidemiology · 1,135

Rare-Variant Association Analysis: Study Designs and Statistical Tests

2014 · Seunggeun Lee, Gonçalo R. Abecasis, et al. · The American Journal of Human Genetics · 1,040

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Genome partitioning of genetic variation for complex traits using common SNPs

2011 · Jian Yang, Teri A Manolio, et al. · Nature Genetics · 888

Efficient multivariate linear mixed model algorithms for genome-wide association studies

2014 · Xiang Zhou, Matthew Stephens · Nature Methods · 839

Assessing the impact of population stratification on genetic association studies

2004 · Matthew L Freedman, David Reich, et al. · Nature Genetics · 807

STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement

2009 · Julian Little, Julian P.T Higgins, et al. · PLoS Medicine · 804

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Works count: 3,363

Citation count: 180,200