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Keyword

PPAR agonists

Description: Compounds that activate peroxisome proliferator-activated receptors, nuclear receptors studied as targets in metabolic and other diseases.
Wikidata ID: wiki/Q10331450
OpenAlex ID: keywords/ppar-agonists
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
2014 · Michal Pawlak, Philippe Lefebvre, et al. · Journal of Hepatology · 1,572
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Liver fibrosis
2005 · R. Bataller · Journal of Clinical Investigation · 1,472
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Anti-inflammatory Agents: Present and Future
2010 · Charles A. Dinarello · Cell · 1,093
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The peroxisome proliferator-activated receptor: A family of nuclear receptors role in various diseases
2011 · Sandeep Tyagi, Paras Gupta, et al. · Journal of Advanced Pharmaceutical Technology amp Research · 1,015
PPAR control of metabolism and cardiovascular functions
2021 · David Montaigne, Laura Butruille, et al. · Nature Reviews Cardiology · 944
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PPAR and human metabolic disease
2006 · R. K. Semple · Journal of Clinical Investigation · 829
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A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH
2021 · Sven M. Francque, Pierre Bedossa, et al. · New England Journal of Medicine · 790
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The Toxicology of Perfluorooctanoate
2004 · Gerald L. Kennedy, John L. Butenhoff, et al. · Critical Reviews in Toxicology · 740
Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases
2017 · Varman T. Samuel, Gerald I. Shulman · Cell Metabolism · 739
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Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ
2004 · Andrew C. Li, Christoph J. Binder, et al. · Journal of Clinical Investigation · 573
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Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease – novel insights into cellular communication circuits
2022 · Moritz Peiseler, Robert Schwabe, et al. · Journal of Hepatology · 555
Role of PPAR receptor in different diseases and their ligands: Physiological importance and clinical implications
2019 · Agha Zeeshan Mirza, Ismail I. Althagafi, et al. · European Journal of Medicinal Chemistry · 544
Modulation of Insulin Resistance in Nonalcoholic Fatty Liver Disease
2018 · Reenam S. Khan, Fernando Bril, et al. · Hepatology · 542
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PPARδ regulates glucose metabolism and insulin sensitivity
2006 · Chih-Hao Lee, Peter Olson, et al. · Proceedings of the National Academy of Sciences · 497
The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention
2012 · Jeffrey M. Peters, Yatrik M. Shah, et al. · Nature reviews. Cancer · 494
Peroxisome proliterator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis
1999 · Jean-Charles Fruchart, Patrick Duriez, et al. · Current Opinion in Lipidology · 427
Endothelial Cell Apoptosis Induced by the Peroxisome Proliferator-activated Receptor (PPAR) Ligand 15-Deoxy-Δ12,14-prostaglandin J2
1999 · David Bishop-Bailey, Timothy Hla · Journal of Biological Chemistry · 424
PPARα: Energy Combustion, Hypolipidemia, Inflammation and Cancer
2010 · Sean R. Pyper, Navin Viswakarma, et al. · Nuclear Receptor Signaling · 381
Peroxisome Proliferator-Activated Receptor Targets for the Treatment of Metabolic Diseases
2013 · Francisco A. Monsalve, Radha D. Pyarasani, et al. · Mediators of Inflammation · 354
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Peroxisome Proliferator–Activated Receptors as Transcriptional Nodal Points and Therapeutic Targets
2007 · Jonathan D. Brown, Jorge Plutzky · Circulation · 341
OXPAT/PAT-1 Is a PPAR-Induced Lipid Droplet Protein That Promotes Fatty Acid Utilization
2006 · Nathan E. Wolins, Benjamin K. Quaynor, et al. · Diabetes · 328
The Novel Role of PPAR Alpha in the Brain: Promising Target in Therapy of Alzheimer’s Disease and Other Neurodegenerative Disorders
2020 · Sylwia Wójtowicz, Anna K. Strosznajder, et al. · Neurochemical Research · 327
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PPARs in the brain
2007 · M HENEKA, G LANDRETH · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 317
Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors
2020 · Sven Francque, Gyongyi Szabo, et al. · Nature Reviews Gastroenterology & Hepatology · 314
Safety issues and prospects for future generations of PPAR modulators
2007 · A RUBENSTRUNK, R HANF, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 309
Works count: 2,148
Citation count: 58,030
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