Keyword

prion replication

Description: The propagation of prions through conversion of normal prion protein into disease-associated forms in biological systems.

Primary topic: Prion Diseases and Protein Misfolding (96%)

OpenAlex ID: keywords/prion-replication

Cell-free formation of protease-resistant prion protein

1994 · David A. Kocisko, Jon H. Come, et al. · Nature · 883

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication

1990 · Stanley B. Prusiner, Michael Scott, et al. · Cell · 871

Does the Agent of Scrapie Replicate without Nucleic Acid ?

1967 · TIKVAH ALPER, W. A. CRAMP, et al. · Nature · 691

Prion biology and diseases.

1994 · S B Prusiner · PubMed · 639

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

2012 · Julie A. Moreno, Helois Radford, et al. · Nature · 614

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

2013 · Julie A. Moreno, Mark Halliday, et al. · Science Translational Medicine · 589

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

2001 · David Peretz, R. Anthony Williamson, et al. · Nature · 525

Prions: Protein Aggregation and Infectious Diseases

2009 · Adriano Aguzzi, Anna Maria Calella · Physiological Reviews · 504

Monoclonal antibodies inhibit prion replication and delay the development of prion disease

2003 · Anthony R. White, Perry Enever, et al. · Nature · 492

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Structural Clues to Prion Replication

1994 · Fred E. Cohen, Keh-Ming Pan, et al. · Science · 471

Caspase‐12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein

2003 · Claudio Hetz, Milene Russelakis‐Carneiro, et al. · The EMBO Journal · 397

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Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein

2001 · Gerold Schmitt-Ulms, Giuseppe Legname, et al. · Journal of Molecular Biology · 388

Creutzfeldt–Jakob Disease and Related Transmissible Spongiform Encephalopathies

1998 · Richard T. Johnson, Clarence J. Gibbs · New England Journal of Medicine · 373

Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

1988 · D A Butler, M R Scott, et al. · Journal of Virology · 366

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Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells

1999 · K.L. Brown, K. Stewart, et al. · Nature Medicine · 363

Impaired Prion Replication in Spleens of Mice Lacking Functional Follicular Dendritic Cells

2000 · Fabio Montrasio, Rico Frigg, et al. · Science · 357

Ultra-efficient Replication of Infectious Prions by Automated Protein Misfolding Cyclic Amplification

2006 · Paula Saá, Joaquín Castilla, et al. · Journal of Biological Chemistry · 328

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Developmental expression of the prion protein gene in glial cells

1995 · Markus Moser, Raymond J Colello, et al. · Neuron · 322

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Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.

1994 · G C Telling, M Scott, et al. · Proceedings of the National Academy of Sciences · 315

Species-barrier-independent prion replication in apparently resistant species

2000 · Andrew F. Hill, Susan Joiner, et al. · Proceedings of the National Academy of Sciences · 295

A systems approach to prion disease

2009 · Daehee Hwang, Inyoul Y Lee, et al. · Molecular Systems Biology · 287

Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie

1989 · M.E. Bruce, P.A. McBride, et al. · Neuroscience Letters · 277

Glycosylation differences between the normal and pathogenic prion protein isoforms

1999 · Pauline M. Rudd, Tama Endo, et al. · Proceedings of the National Academy of Sciences · 273

Prion Protein Devoid of the Octapeptide Repeat Region Restores Susceptibility to Scrapie in PrP Knockout Mice

2000 · Eckhard Flechsig, Doron Shmerling, et al. · Neuron · 257

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Normal host prion protein (PrP C ) is required for scrapie spread within the central nervous system

1996 · Sebastian Brandner, Alex Raeber, et al. · Proceedings of the National Academy of Sciences · 252

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Works count: 776

Citation count: 32,080