Keyword

prions

Description: Infectious agents composed of misfolded proteins that propagate abnormal protein folding and cause diseases in humans and other animals.

Primary topic: Prion Diseases and Protein Misfolding (72%)

Wikidata ID: wiki/Q47051

OpenAlex ID: keywords/prions

Prions

1998 · Stanley B. Prusiner · Proceedings of the National Academy of Sciences · 5,368

Novel Proteinaceous Infectious Particles Cause Scrapie

1982 · Stanley B. Prusiner · Science · 5,121

Risk factors for human disease emergence

2001 · Louise H. Taylor, Sophia M. Latham, et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 2,832

Structure of the cross-β spine of amyloid-like fibrils

2005 · Rebecca Nelson, Michael R. Sawaya, et al. · Nature · 2,204

Clinical veterinary microbiology

1994 · Peter Quinn · Wolfe eBooks · 1,463

Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding

2001 · Gabriela P. Saborio, Bruno Permanne, et al. · Nature · 1,310

Identification of a Protein That Purifies with the Scrapie Prion

1982 · David C. Bolton, Michael P. McKinley, et al. · Science · 1,281

Nature of the Scrapie Agent: Self-replication and Scrapie

1967 · J. S. GRIFFITH · Nature · 1,161

A General Model of Prion Strains and Their Pathogenicity

2007 · John Collinge, Anthony R. Clarke · Science · 1,057

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

2009 · Samir K. Maji, Marilyn H. Perrin, et al. · Science · 1,051

Amyloid Fibrils of the HET-s(218–289) Prion Form a β Solenoid with a Triangular Hydrophobic Core

2008 · Christian Wasmer, Adam Lange, et al. · Science · 998

Cells release prions in association with exosomes

2004 · Benoit Fevrier, Didier Vilette, et al. · Proceedings of the National Academy of Sciences · 997

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A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

2009 · Simon Alberti, Randal Halfmann, et al. · Cell · 973

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Prion Diseases and the BSE Crisis

1997 · Stanley B. Prusiner · Science · 955

Exosomes: A Common Pathway for a Specialized Function

2006 · Guillaume van Niel, Isabel Porto-Carreiro, et al. · The Journal of Biochemistry · 922

A protease-resistant protein is a structural component of the Scrapie prion

1983 · Michael P. McKinley, David C. Bolton, et al. · Cell · 918

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2015 · EFSA Scientific Committee · EFSA Journal · 806

In Vitro Generation of Infectious Scrapie Prions

2005 · Joaquín Castilla, Paula Saá, et al. · Cell · 790

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Inflammasomes in neuroinflammatory and neurodegenerative diseases

2019 · Sofie Voet, Sahana Srinivasan, et al. · EMBO Molecular Medicine · 756

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Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

2015 · Stanley B. Prusiner, Amanda L. Woerman, et al. · Proceedings of the National Academy of Sciences · 691

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Does the Agent of Scrapie Replicate without Nucleic Acid ?

1967 · TIKVAH ALPER, W. A. CRAMP, et al. · Nature · 691

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

2010 · Fei Wang, Xinhe Wang, et al. · Science · 661

Prion biology and diseases.

1994 · S B Prusiner · PubMed · 639

Prions hijack tunnelling nanotubes for intercellular spread

2009 · Karine Gousset, Edwin Schiff, et al. · Nature Cell Biology · 615

PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition

2014 · Alex K. Lancaster, Andrew Nutter-Upham, et al. · Bioinformatics · 594

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Works count: 5,249

Citation count: 112,100