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Keyword

PRMT4

Description: PRMT4, also called CARM1, is a protein arginine methyltransferase enzyme involved in methylation and studied in molecular biology and disease research.
Wikidata ID: wiki/Q18035436
OpenAlex ID: keywords/prmt4
The Novel Human Protein Arginine N-Methyltransferase PRMT6 Is a Nuclear Enzyme Displaying Unique Substrate Specificity
2002 · Adam Frankel, Neelu Yadav, et al. · Journal of Biological Chemistry · 334
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Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells
2016 · Sara C. Larsen, Kathrine B. Sylvestersen, et al. · Science Signaling · 322
PRMT4 promotes ferroptosis to aggravate doxorubicin-induced cardiomyopathy via inhibition of the Nrf2/GPX4 pathway
2022 · Yilong Wang, Shu Yan, et al. · Cell Death and Differentiation · 316
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A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases
2015 · Mohammad S. Eram, Yudao Shen, et al. · ACS Chemical Biology · 292
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Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice
2003 · Neelu Yadav, Jaeho Lee, et al. · Proceedings of the National Academy of Sciences · 287
The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans
2009 · S. S. Wolf · Cellular and Molecular Life Sciences · 232
Arginine Methylation of MDH1 by CARM1 Inhibits Glutamine Metabolism and Suppresses Pancreatic Cancer
2016 · Yi-Ping Wang, Wei Zhou, et al. · Molecular Cell · 226
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Arginine methyltransferase CARM1 is a promoter‐specific regulator of NF‐κB‐dependent gene expression
2004 · Marcela Covic, Paul O Hassa, et al. · The EMBO Journal · 223
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Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth
2021 · Wen-juan Li, Yao-hui He, et al. · Nature Communications · 192
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The Coactivator-associated Arginine Methyltransferase Is Necessary for Muscle Differentiation
2002 · Shen Liang Chen, Kelly A. Loffler, et al. · Journal of Biological Chemistry · 163
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CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer
2018 · Xing-Yu Zhong, Xiu-Ming Yuan, et al. · Cell Reports · 158
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TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma
2018 · Kazuhide Nakayama, Magdalena M. Szewczyk, et al. · Oncotarget · 152
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Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition
2017 · Evgenia Shishkova, Hao Zeng, et al. · Nature Communications · 141
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Arginine methylation‐dependent LSD1 stability promotes invasion and metastasis of breast cancer
2019 · Jiwei Liu, Jingxin Feng, et al. · EMBO Reports · 122
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PRMT4 Blocks Myeloid Differentiation by Assembling a Methyl-RUNX1-Dependent Repressor Complex
2013 · Ly P. Vu, Fabiana Perna, et al. · Cell Reports · 114
CARM1/PRMT4: Making Its Mark beyond Its Function as a Transcriptional Coactivator
2021 · Samyuktha Suresh, Solène Huard, et al. · Trends in Cell Biology · 105
Identification of a Novel Inhibitor of Coactivator-associated Arginine Methyltransferase 1 (CARM1)-mediated Methylation of Histone H3 Arg-17
2009 · B. Ruthrotha Selvi, Kiran Batta, et al. · Journal of Biological Chemistry · 95
Vascular Smooth Muscle LRP6 Limits Arteriosclerotic Calcification in Diabetic LDLR −/− Mice by Restraining Noncanonical Wnt Signals
2015 · Su-Li Cheng, Bindu Ramachandran, et al. · Circulation Research · 93
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Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response
2015 · Kerstin Hein, Gerhard Mittler, et al. · Science Signaling · 93
CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells
2010 · Karen B. O'Brien, Meritxell Alberich-Jordà, et al. · Development · 90
Assay Development for Histone Methyltransferases
2013 · Kurumi Y. Horiuchi, Mia M. Eason, et al. · Assay and Drug Development Technologies · 81
Are STATS Arginine-methylated?
2005 · Waraporn Komyod, Uta-Maria Bauer, et al. · Journal of Biological Chemistry · 73
A hypermethylation strategy utilized by enhancer-bound CARM1 to promote estrogen receptor α-dependent transcriptional activation and breast carcinogenesis
2020 · Bing-ling Peng, Wen-juan Li, et al. · Theranostics · 72
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Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification
2009 · Tatsuo Ito, Neelu Yadav, et al. · BMC Developmental Biology · 71
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High-glucose-induced CARM1 expression regulates apoptosis of human retinal pigment epithelial cells via histone 3 arginine 17 dimethylation: Role in diabetic retinopathy
2014 · Dong-il Kim, Min-jung Park, et al. · Archives of Biochemistry and Biophysics · 70
Works count: 228
Citation count: 5,934
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