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Keyword

PRMT6

Description: A protein arginine methyltransferase encoded by a human gene, involved in modifying proteins and studied in molecular biology and disease research.
Wikidata ID: wiki/Q18041615
OpenAlex ID: keywords/prmt6
Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive
2007 · Ernesto Guccione, Christian Bassi, et al. · Nature · 492
The Novel Human Protein Arginine N-Methyltransferase PRMT6 Is a Nuclear Enzyme Displaying Unique Substrate Specificity
2002 · Adam Frankel, Neelu Yadav, et al. · Journal of Biological Chemistry · 334
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Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers
2010 · Masanori Yoshimatsu, Gouji Toyokawa, et al. · International Journal of Cancer · 313
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PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation
2007 · Dawin Hyllus, Claudia Stein, et al. · Genes & Development · 306
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A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases
2015 · Mohammad S. Eram, Yudao Shen, et al. · ACS Chemical Biology · 292
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Pancreatic β Cell Identity Is Maintained by DNA Methylation-Mediated Repression of Arx
2011 · Sangeeta Dhawan, Senta Georgia, et al. · Developmental Cell · 262
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A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation
2012 · Andrea D. Coviello, Robin Haring, et al. · PLoS Genetics · 250
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The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans
2009 · S. S. Wolf · Cellular and Molecular Life Sciences · 232
Arginine Methylation of the Histone H3 Tail Impedes Effector Binding
2007 · Aimee N. Iberg, Alexsandra Espejo, et al. · Journal of Biological Chemistry · 203
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Methylation of Tat by PRMT6 Regulates Human Immunodeficiency Virus Type 1 Gene Expression
2004 · Marie-Chloé Boulanger, Chen Liang, et al. · Journal of Virology · 199
Arginine Methylation Regulates DNA Polymerase β
2006 · Nazim El-Andaloussi, Taras Valovka, et al. · Molecular Cell · 193
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A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia
2011 · Zhibin Hu, Yankai Xia, et al. · Nature Genetics · 164
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6
2019 · Yuhong Luo, Cen Xie, et al. · Gastroenterology · 154
H3R42me2a is a histone modification with positive transcriptional effects
2013 · Fabio Casadio, Xiangdong Lu, et al. · Proceedings of the National Academy of Sciences · 153
Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound
2015 · Lorna H. Mitchell, Allison E. Drew, et al. · ACS Medicinal Chemistry Letters · 139
PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
2021 · Tianzhi Huang, Yongyong Yang, et al. · Molecular Cell · 138
Arginine Methylation of the Human Immunodeficiency Virus Type 1 Tat Protein by PRMT6 Negatively Affects Tat Interactions with both Cyclin T1 and the Tat Transactivation Region
2007 · Baode Xie, Cédric F. Invernizzi, et al. · Journal of Virology · 136
A mycobacterial effector promotes ferroptosis-dependent pathogenicity and dissemination
2023 · Lihua Qiang, Yong Zhang, et al. · Nature Communications · 134
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CRAF Methylation by PRMT6 Regulates Aerobic Glycolysis–Driven Hepatocarcinogenesis via ERK‐Dependent PKM2 Nuclear Relocalization and Activation
2019 · Tin‐Lok Wong, Kai‐Yu Ng, et al. · Hepatology · 131
Skeletal muscle-specific Prmt1 deletion causes muscle atrophy via deregulation of the PRMT6-FOXO3 axis
2019 · Seri Choi, Hyeon-Ju Jeong, et al. · Autophagy · 131
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Protein Arginine Methyltransferases: from Unicellular Eukaryotes to Humans
2007 · François Bachand · Eukaryotic Cell · 131
Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor
2012 · Mathieu Neault, Frédérick A. Mallette, et al. · Nucleic Acids Research · 119
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PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation
2018 · Lok Hei Chan, Lei Zhou, et al. · Cell Reports · 115
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Genomewide Association Study of a Rapid Progression Cohort Identifies New Susceptibility Alleles for AIDS (ANRS Genomewide Association Study 03)
2009 · Sigrid Le Clerc, Sophie Limou, et al. · The Journal of Infectious Diseases · 109
The Role of Protein Arginine Methyltransferases in Inflammatory Responses
2016 · Ji Hye Kim, Byong Chul Yoo, et al. · Mediators of Inflammation · 105
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Works count: 459
Citation count: 10,800
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