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Keyword

PTRF

Description: A human gene encoding cavin-1, a protein involved in caveola formation and also known for its role in transcription-complex release.
Wikidata ID: wiki/Q18054260
OpenAlex ID: keywords/ptrf
PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function
2008 · Michelle M. Hill, Michele Bastiani, et al. · Cell · 739
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Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy
2009 · Yukiko K. Hayashi, Chie Matsuda, et al. · Journal of Clinical Investigation · 395
A Critical Role of Cavin (Polymerase I and Transcript Release Factor) in Caveolae Formation and Organization
2007 · Libin Liu, Paul F. Pilch · Journal of Biological Chemistry · 275
Congenital generalized lipodystrophies—new insights into metabolic dysfunction
2015 · Nivedita Patni, Abhimanyu Garg · Nature Reviews Endocrinology · 261
SDPR induces membrane curvature and functions in the formation of caveolae
2009 · Carsten G. Hansen, Nicholas A. Bright, et al. · Nature Cell Biology · 257
SRBC/cavin‐3 is a caveolin adapter protein that regulates caveolae function
2009 · Kerrie‐Ann McMahon, Hubert Zajicek, et al. · The EMBO Journal · 205
Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes
2004 · Nabila ABOULAICH, Julia P. VAINONEN, et al. · Biochemical Journal · 163
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Caveolae structure and function
2008 · Candice M. Thomas, Eric J. Smart · Journal of Cellular and Molecular Medicine · 155
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Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes
1998 · Petr Jansa, Stephen W. Mason, et al. · The EMBO Journal · 153
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Blood exosomes-based targeted delivery of cPLA2 siRNA and metformin to modulate glioblastoma energy metabolism for tailoring personalized therapy
2022 · Qi Zhan, Kaikai Yi, et al. · Neuro-Oncology · 116
Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS
2008 · Udayan Guha, Raghothama Chaerkady, et al. · Proceedings of the National Academy of Sciences · 112
Neuronal STAT3/HIF-1α/PTRF axis-mediated bioenergetic disturbance exacerbates cerebral ischemia-reperfusion injury via PLA2G4A
2022 · Weili Jin, Jixing Zhao, et al. · Theranostics · 103
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Cavin‐1/PTRF alters prostate cancer cell‐derived extracellular vesicle content and internalization to attenuate extracellular vesicle‐mediated osteoclastogenesis and osteoblast proliferation
2014 · Kerry L. Inder, Jayde E. Ruelcke, et al. · Journal of Extracellular Vesicles · 103
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Polymerase Transcriptase Release Factor (PTRF) Anchors MG53 Protein to Cell Injury Site for Initiation of Membrane Repair
2011 · Hua Zhu, Peihui Lin, et al. · Journal of Biological Chemistry · 102
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Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells
2017 · Francesca Stillitano, Jens Hansen, et al. · eLife · 100
Identification of a major protein on the cytosolic face of caveolae
2005 · J. Vinten, A.H. Johnsen, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 92
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Exploring the pathophysiology behind the more common genetic and acquired lipodystrophies
2013 · Tom Nolis · Journal of Human Genetics · 87
Mechanism of transcription termination: PTRF interacts with the largest subunit of RNA polymerase I and dissociates paused transcription complexes from yeast and mouse
1999 · P. Jansa, I. Grummt · Molecular and General Genetics MGG · 85
PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer
2013 · H Moon, C S Lee, et al. · Oncogene · 78
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Integrated Analysis of RNA-Binding Proteins in Glioma
2020 · Zhixing Wang, Wanjun Tang, et al. · Cancers · 73
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Down‐regulation of the cavin family proteins in breast cancer
2011 · Lin Bai, Xiaoli Deng, et al. · Journal of Cellular Biochemistry · 73
Astragalus polysaccharide alleviates alcoholic-induced hepatic fibrosis by inhibiting polymerase I and transcript release factor and the TLR4/JNK/NF-κB/MyD88 pathway
2023 · Xu Sun, Yongqiu Zheng, et al. · Journal of Ethnopharmacology · 72
Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system
2022 · Fidel-Nicolás Lolo, Nikhil Walani, et al. · Nature Cell Biology · 72
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Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1
2011 · Lin Bai, Xiaoli Deng, et al. · Cell Research · 69
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Expression of PTRF in PC-3 Cells Modulates Cholesterol Dynamics and the Actin Cytoskeleton Impacting Secretion Pathways
2011 · Kerry L. Inder, Yu Zi Zheng, et al. · Molecular & Cellular Proteomics · 67
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Works count: 203
Citation count: 6,060
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