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Keyword

pyrogens

Description: Substances that induce fever by triggering temperature-regulating responses in the body, including microbial contaminants relevant to injectable medicines.
Wikidata ID: wiki/Q50430141
OpenAlex ID: keywords/pyrogens
Fever and the thermal regulation of immunity: the immune system feels the heat
2015 · Sharon S. Evans, Elizabeth A. Repasky, et al. · Nature reviews. Immunology · 1,265
Fever: Role of Pyrogens and Cryogens
1991 · Matthew J. Kluger · Physiological Reviews · 1,216
Role of the Preoptic-Anterior Hypothalamus in Thermoregulation and Fever
2000 · Jack A. Boulant · Clinical Infectious Diseases · 562
Central circuitries for body temperature regulation and fever
2011 · Kazuhiro Nakamura · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 543
Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro.
1987 · C A Dinarello, T Ikejima, et al. · The Journal of Immunology · 537
Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice
1995 · Hui Zheng, Daniel Fletcher, et al. · Immunity · 366
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The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism
2004 · Marie-Eve Fortier, Stephen Kent, et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 354
Profound Neutropenia During the Early Phase of Hemodialysis
1968 · Leonard S. Kaplow · JAMA · 342
Physiology of temperature regulation: Comparative aspects
2006 · Kênia C. Bicego, Renata C.H. Barros, et al. · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · 276
Mechanisms and Mediators of Psychological Stress-Induced Rise in Core Temperature
2001 · Takakazu Oka, Kae Oka, et al. · Psychosomatic Medicine · 271
The febrile response to lipopolysaccharide is blocked in cyclooxygenase-2−/−, but not in cyclooxygenase-1−/− mice
1999 · S Li, Y Wang, et al. · Brain Research · 270
Studies on the Pathogenesis of Fever
1953 · Ivan L. Bennett, Paul B. Beeson, et al. · The Journal of Experimental Medicine · 265
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Concepts of Fever
1998 · Philip A. Mackowiak · Archives of Internal Medicine · 257
Brain Endothelial Cells Express Cyclooxygenase-2 during Lipopolysaccharide-Induced Fever: Light and Electron Microscopic Immunocytochemical Studies
1998 · Kiyoshi Matsumura, Chunyu Cao, et al. · Journal of Neuroscience · 247
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Central efferent pathways for cold‐defensive and febrile shivering
2011 · Kazuhiro Nakamura, Shaun F. Morrison · The Journal of Physiology · 238
Invited Review: Cytokine regulation of fever: studies using gene knockout mice
2002 · Lisa R. Leon · Journal of Applied Physiology · 224
Prostaglandin E as the neural mediator of the febrile response.
1986 · J T Stitt · PubMed · 196
Blockade of lipopolysaccharide-induced fever by subdiaphragmatic vagotomy in guinea pigs
1996 · Elmir Sehic, Clark M. Blatteis · Brain Research · 194
Safety evaluation of exosomes derived from human umbilical cord mesenchymal stromal cell
2016 · Li Sun, Rongman Xu, et al. · Cytotherapy · 182
Observations on the site and mode of action of pyrogens in the rabbit brain
1967 · K. E. Cooper, W. I. Cranston, et al. · The Journal of Physiology · 181
Monoamines, Pyrogens and Cations: Their Actions on Central Control of Body Temperature
1974 · R.F. Hellon · Pharmacological Reviews · 180
Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain
2006 · Christoph Rummel, Christelle Sachot, et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 179
Effect of pyrogen and antipyretics on prostaglandin activity in cisternal c.s.f. of unanaesthetized cats
1973 · W. Feldberg, K. P. Gupta, et al. · The Journal of Physiology · 165
Inactivation of Bacteria and Biomolecules by Low‐Pressure Plasma Discharges
2010 · A. von Keudell, P. Awakowicz, et al. · Plasma Processes and Polymers · 158
Recent advances in biosensor based endotoxin detection
2013 · A.P. Das, P.S. Kumar, et al. · Biosensors and Bioelectronics · 156
Works count: 1,517
Citation count: 24,540
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