Keyword

Rac1

Description: Rac1 is a small Rho-family GTPase that regulates actin organization, cell movement, and signaling in cellular and biomedical research.

Primary topic: Protein Kinase Regulation and GTPase Signaling (22%)

OpenAlex ID: keywords/rac1

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 · Anne J. Ridley, Hugh F. Paterson, et al. · Cell · 3,653

A Landscape of Driver Mutations in Melanoma

2012 · Eran Hodis, Ian R. Watson, et al. · Cell · 2,606

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Rho GTPases and signaling networks

1997 · Linda Van Aelst, Crislyn D’Souza-Schorey · Genes & Development · 2,358

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The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

1995 · Omar A. Coso, Mario Chiariello, et al. · Cell · 1,629

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Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts

1997 · Kaikobad Irani, Yong Xia, et al. · Science · 1,588

The orphan receptor GPR55 is a novel cannabinoid receptor

2007 · E Ryberg, N Larsson, et al. · British Journal of Pharmacology · 1,569

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 · Edward Manser, Thomas Leung, et al. · Nature · 1,538

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

2010 · Yingdi Wang, Masanori Nakayama, et al. · Nature · 1,276

The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

1995 · Caroline S. Hill, Judy Wynne, et al. · Cell · 1,269

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Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.

1995 · S Miyamoto, H Teramoto, et al. · The Journal of Cell Biology · 1,203

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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

2012 · Michael Krauthammer, Yong Kong, et al. · Nature Genetics · 1,191

Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

2006 · Anne J. Ridley · Trends in Cell Biology · 1,180

1995 · Robert Kozma, Sohail Ahmed, et al. · Molecular and Cellular Biology · 1,021

Regulation of the Cytoskeleton and Cell Adhesion by the Rho Family GTPases in Mammalian Cells

1999 · K. Kaibuchi, S. Kuroda, et al. · Annual Review of Biochemistry · 1,017

Coordination of Rho GTPase activities during cell protrusion

2009 · Matthias Machacek, Louis Hodgson, et al. · Nature · 1,000

A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation

2005 · Na Kyung Lee, Young Geum Choi, et al. · Blood · 959

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Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

2010 · Mirkka Koivusalo, Christopher Welch, et al. · The Journal of Cell Biology · 891

An essential role for Rac in Ras transformation

1995 · Rong-Guo Qiu, Jing Chen, et al. · Nature · 882

Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck

2002 · Sharon Eden, Rajat Rohatgi, et al. · Nature · 848

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

2014 · Ovijit Chaudhuri, Sandeep T. Koshy, et al. · Nature Materials · 820

S. typhimurium Encodes an Activator of Rho GTPases that Induces Membrane Ruffling and Nuclear Responses in Host Cells

1998 · Wolf-Dietrich Hardt, Li-Mei Chen, et al. · Cell · 811

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Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

2015 · Matthew T Chang, Saurabh Asthana, et al. · Nature Biotechnology · 807

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 · A.J. Ridley, H.F. Paterson, et al. · Trends in Cell Biology · 756

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1997 · Piero Crespo, Kornel E. Schuebel, et al. · Nature · 755

PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors

1998 · Edward Manser, Tsui-Han Loo, et al. · Molecular Cell · 753

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Works count: 13,550

Citation count: 504,100