Keyword

radiotracer synthesis

Description: Radiotracer synthesis is the chemical preparation of radioactive compounds used to track biological or chemical processes, especially in medical imaging and research.

Primary topic: Radiopharmaceutical Chemistry and Applications (71%)

Wikidata ID: wiki/Q20155580

OpenAlex ID: keywords/radiosynthesis

68Ga- and 177Lu-Labeled PSMA I&T: Optimization of a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies

2015 · Martina Weineisen, Margret Schottelius, et al. · Journal of Nuclear Medicine · 535

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Fluorine-18 Radiochemistry, Labeling Strategies and Synthetic Routes

2014 · Orit Jacobson, Dale O. Kiesewetter, et al. · Bioconjugate Chemistry · 503

Labeled 2‐deoxy‐D‐glucose analogs. 18 F‐labeled 2‐deoxy‐2‐fluoro‐D‐glucose, 2‐deoxy‐2‐fluoro‐D‐mannose and 14 C‐2‐deoxy‐2‐fluoro‐D‐glucose

1978 · T. Ido, C‐N. Wan, et al. · Journal of Labelled Compounds and Radiopharmaceuticals · 434

A General Copper‐Mediated Nucleophilic 18 F Fluorination of Arenes

2014 · Matthew Tredwell, Sean M. Preshlock, et al. · Angewandte Chemie International Edition · 388

Chemistry for Positron Emission Tomography: Recent Advances in 11 C‐, 18 F‐, 13 N‐, and 15 O‐Labeling Reactions

2018 · Xiaoyun Deng, Jian Rong, et al. · Angewandte Chemie International Edition · 359

Radiolabeled Cyclic RGD Peptides as Integrin αvβ3-Targeted Radiotracers: Maximizing Binding Affinity via Bivalency

2009 · Shuang Liu · Bioconjugate Chemistry · 344

A simple synthesis of [11C]methyl triflate

1992 · Douglas M. Jewett · International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes · 343

[18F]Galacto-RGD: Synthesis, Radiolabeling, Metabolic Stability, and Radiation Dose Estimates

2003 · Roland Haubner, Bertrand Kuhnast, et al. · Bioconjugate Chemistry · 324

Synthesis and Preclinical Evaluation of 11 C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

2016 · Nabeel B. Nabulsi, Joël Mercier, et al. · Journal of Nuclear Medicine · 296

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Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin α v β 3

2015 · Haojun Chen, Gang Niu, et al. · Theranostics · 282

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Principles of Nuclear Medicine

1976 · IEEE Transactions on Nuclear Science · 265

Synthesis of [11C]iodomethane by iodination of [11C]methane

1997 · Peter Larsen, Johan Ulin, et al. · Applied Radiation and Isotopes · 255

Synthesis of [18F]Arenes via the Copper-Mediated [18F]Fluorination of Boronic Acids

2015 · Andrew V. Mossine, Allen F. Brooks, et al. · Organic Letters · 251

Novel Radiotracers for Imaging the Serotonin Transporter by Positron Emission Tomography: Synthesis, Radiosynthesis, and in Vitro and ex Vivo Evaluation of 11C-Labeled 2-(Phenylthio)araalkylamines

2000 · Alan A. Wilson, Nathalie Ginovart, et al. · Journal of Medicinal Chemistry · 249

Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics

2014 · Benjamin H. Rotstein, Nickeisha A. Stephenson, et al. · Nature Communications · 243

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Radiosynthesis and Evaluation of [11C]-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a Potential Radiotracer for in Vivo Imaging of the Dopamine D2 High-Affinity State with Positron Emission Tomography

2005 · Alan A. Wilson, Patrick McCormick, et al. · Journal of Medicinal Chemistry · 227

Regioselective radiofluorodestannylation with [18F]F2 and [18F]CH3COOF: A high yield synthesis of 6-[18F]fluoro-l-dopa

1992 · Mohammad Namavari, Allyson Bishop, et al. · International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes · 223

Fluorinated benzamide neuroleptics—III. Development of (S)-N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-2,3-dimethoxybenzamide as an improved dopamine D-2 receptor tracer

1995 · Jogeshwar Mukherjee, Zhi-Ying Yang, et al. · Nuclear Medicine and Biology · 219

Promising Prospects for 44Sc-/47Sc-Based Theragnostics: Application of 47Sc for Radionuclide Tumor Therapy in Mice

2014 · Cristina Müller, Maruta Bunka, et al. · Journal of Nuclear Medicine · 214

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Development of (18)F-fluoroethylcholine for cancer imaging with PET: synthesis, biochemistry, and prostate cancer imaging.

2002 · Toshihiko Hara, Noboru Kosaka, et al. · PubMed · 214

Radiosynthesis of 3′-deoxy-3′-[18F]fluorothymidine: [18F]FLT for imaging of cellular proliferation in vivo

2000 · John R Grierson, Anthony F Shields · Nuclear Medicine and Biology · 214

Derisking the Cu-Mediated 18F-Fluorination of Heterocyclic Positron Emission Tomography Radioligands

2017 · Nicholas J. Taylor, Enrico Emer, et al. · Journal of the American Chemical Society · 213

Synthesis of L- and D-[methyl-11C]methionine.

1987 · B Långström, G Antoni, et al. · PubMed · 213

18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis

2004 · Xiaoyuan Chen, Ryan Park, et al. · Nuclear Medicine and Biology · 212

Labelling and metabolism of methionine-methyl-11C

1976 · Dominique Comar, Jean-Claude Cartron, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 212

Works count: 7,133

Citation count: 81,020