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Keyword

RARα

Description: A retinoic acid receptor alpha protein that regulates gene expression in response to retinoids and is studied in molecular biology and cancer research.
Wikidata ID: wiki/Q18031040
OpenAlex ID: keywords/raralpha
The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus
1990 · Hugues de Thé, Christine Chomienne, et al. · Nature · 1,355
Role of the histone deacetylase complex in acute promyelocytic leukaemia
1998 · Richard J. Lin, Laszlo Nagy, et al. · Nature · 1,062
Identification of a second human retinoic acid receptor
1988 · Nigel Brand, Martin Petkovich, et al. · Nature · 1,022
Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin
1989 · Arthur Zelent, Andrée Krust, et al. · Nature · 793
Retinoic acid receptors and cellular retinoid binding proteins: I. A systematic study of their differential pattern of transcription during mouse organogenesis
1990 · Pascal Dollé, Esther Ruberte, et al. · Development · 574
Retinoic acid receptors and cellular retinoid binding proteins : II. Their differential pattern of transcription during early morphogenesis in mouse embryos
1991 · Esther Ruberte, Pascal Dolle, et al. · Development · 516
Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse
1989 · Pascal Dollé, Esther Ruberte, et al. · Nature · 474
A PMLRAR α transgene initiates murine acute promyelocytic leukemia
1997 · Diane Brown, Scott Kogan, et al. · Proceedings of the National Academy of Sciences · 434
Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development
1997 · Philippe Kastner, Manuel Mark, et al. · Development · 429
Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins.
1992 · P. Kastner, A. Perez, et al. · The EMBO Journal · 415
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Crystal Structure of a Heterodimeric Complex of RAR and RXR Ligand-Binding Domains
2000 · William Bourguet, Valérie Vivat, et al. · Molecular Cell · 404
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International Union of Pharmacology. LX. Retinoic Acid Receptors
2006 · Pierre Germain, Pierre Chambon, et al. · Pharmacological Reviews · 397
Isolation and Characterization of PBP, a Protein That Interacts with Peroxisome Proliferator-activated Receptor
1997 · Yijun Zhu, Chao Qi, et al. · Journal of Biological Chemistry · 346
Acute leukemia with promyelocytic features in PML/RARα transgenic mice
1997 · Li-Zhen He, Carla Tribioli, et al. · Proceedings of the National Academy of Sciences · 340
H2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-Renewal and Differentiation
2012 · Gangqing Hu, Kairong Cui, et al. · Cell stem cell · 338
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Retinoic Acid Receptor β Mediates the Growth-Inhibitory Effect of Retinoic Acid by Promoting Apoptosis in Human Breast Cancer Cells
1996 · Yi Liu, Mi-Ock Lee, et al. · Molecular and Cellular Biology · 329
Transcriptional regulation of granulocyte and monocyte development
2002 · Alan D Friedman · Oncogene · 324
Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).
1990 · S J Collins, K A Robertson, et al. · Molecular and Cellular Biology · 318
Stimulation of RARα Activation Function AF-1 through Binding to the General Transcription Factor TFIIH and Phosphorylation by CDK7
1997 · Cécile Rochette-Egly, Sylvie Adam, et al. · Cell · 308
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A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene.
1989 · G W Vasios, J D Gold, et al. · Proceedings of the National Academy of Sciences · 307
Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties.
1991 · P P Pandolfi, F Grignani, et al. · PubMed · 289
Retinoic acid promotes differentiation of photoreceptors in vitro
1994 · Matthew W. Kelley, Jennifer K. Turner, et al. · Development · 273
Retinoic Acid Receptors and Cancers
2004 · Dianne Robert Soprano, Pu Qin, et al. · Annual Review of Nutrition · 270
RAR‐specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage‐independent cell proliferation.
1995 · J.Y. Chen, S. Penco, et al. · The EMBO Journal · 255
High frequency of retinoic acid receptor beta abnormalities in human lung cancer.
1991 · J F Gebert, N Moghal, et al. · PubMed · 215
Works count: 1,031
Citation count: 36,560
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