Keyword

SELEX

Description: A laboratory method that uses iterative selection and amplification to identify nucleic acid molecules that bind a chosen target with high affinity.

Primary topic: Advanced biosensing and bioanalysis techniques (61%)

Wikidata ID: wiki/Q907101

OpenAlex ID: keywords/selex

Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase

1990 · Craig Tuerk, Larry Gold · Science · 10,418

Aptamers: An Emerging Class of Molecules That Rival Antibodies in Diagnostics

1999 · Sumedha D Jayasena · Clinical Chemistry · 2,145

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New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning

1998 · P.T Lowary, J Widom · Journal of Molecular Biology · 1,779

SELEX—A (r)evolutionary method to generate high-affinity nucleic acid ligands

2007 · Regina Stoltenburg, Christine Reinemann, et al. · Biomolecular Engineering · 1,430

In Vitro Selection of Functional Nucleic Acids

1999 · David S. Wilson, Jack W. Szostak · Annual Review of Biochemistry · 1,208

Analytical applications of aptamers

2004 · S. Tombelli, M. Minunni, et al. · Biosensors and Bioelectronics · 1,017

Analysis of aptamer discovery and technology

2017 · Matthew R. Dunn, Randi M. Jimenez, et al. · Nature Reviews Chemistry · 934

Oligonucleotide inhibitors of human thrombin that bind distinct epitopes

1997 · Diane M Tasset, Mark F Kubik, et al. · Journal of Molecular Biology · 837

Aptamers and Their Biological Applications

2012 · Kyung-Mi Song, Seonghwan Lee, et al. · Sensors · 822

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Electronic Aptamer‐Based Sensors

2007 · Itamar Willner, Maya Zayats · Angewandte Chemie International Edition · 818

Diversity of Oligonucleotide Functions

1995 · Larry Gold, Barry Polisky, et al. · Annual Review of Biochemistry · 809

DNAzymes for sensing, nanobiotechnology and logic gate applications

2008 · Itamar Willner, Bella Shlyahovsky, et al. · Chemical Society Reviews · 791

2′-Fluoropyrimidine RNA-based Aptamers to the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF165)

1998 · Judy Ruckman, Louis S. Green, et al. · Journal of Biological Chemistry · 744

Current approaches in SELEX: An update to aptamer selection technology

2015 · Mariia Darmostuk, Silvie Rimpelova, et al. · Biotechnology Advances · 702

Aptamers come of age – at last

2006 · David H. J. Bunka, Peter G. Stockley · Nature Reviews Microbiology · 701

Recent Advances in Aptamer Discovery and Applications

2019 · Yang Zhang, Bo Shiun Lai, et al. · Molecules · 663

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Aptamers as Therapeutics

2017 · Shahid M. Nimjee, Rebekah R. White, et al. · The Annual Review of Pharmacology and Toxicology · 613

Aptamers as a replacement for antibodies in enzyme-linked immunosorbent assay

2014 · Saw Yi Toh, Marimuthu Citartan, et al. · Biosensors and Bioelectronics · 612

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

2016 · Hong-Min Meng, Hui Liu, et al. · Chemical Society Reviews · 608

Aptamers: molecular tools for analytical applications

2007 · Teresa Mairal, Veli Cengiz Özalp, et al. · Analytical and Bioanalytical Chemistry · 587

A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment

2003 · Dion A. Daniels, Hang Chen, et al. · Proceedings of the National Academy of Sciences · 567

Replacing antibodies with aptamers in lateral flow immunoassay

2015 · Ailiang Chen, Shuming Yang · Biosensors and Bioelectronics · 552

Aptamer-based biosensors for biomedical diagnostics

2014 · Wenhu Zhou, Po-Jung Jimmy Huang, et al. · The Analyst · 540

The Human Transcription Factors

2018 · Samuel A. Lambert, Arttu Jolma, et al. · Cell · 530

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Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

2014 · John C Rohloff, Amy D Gelinas, et al. · Molecular Therapy — Nucleic Acids · 530

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Works count: 4,388

Citation count: 143,000