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Keyword

serpins

Description: Serpins are a protein superfamily of serine protease inhibitors involved in regulating proteolysis across biological processes.
Wikidata ID: wiki/Q420068
OpenAlex ID: keywords/serpins
Human Plasma Proteinase Inhibitors
1983 · J. Travis, G. S. Salvesen · Annual Review of Biochemistry · 2,104
The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins
2001 · Gary A. Silverman, Phillip I. Bird, et al. · Journal of Biological Chemistry · 1,230
Serpin Structure, Mechanism, and Function
2002 · Peter G. W. Gettins · Chemical Reviews · 1,229
Structure of a serpin–protease complex shows inhibition by deformation
2000 · James A. Huntington, Randy J. Read, et al. · Nature · 1,093
Natural protein proteinase inhibitors and their interaction with proteinases
1992 · Wolfram BODE, Robert HUBER · European Journal of Biochemistry · 1,045
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Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme
1992 · Caroline A. Ray, Roy A. Black, et al. · Cell · 978
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
2007 · Tomas Vaisar, Subramaniam Pennathur, et al. · Journal of Clinical Investigation · 944
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Maspin, a Serpin with Tumor-Suppressing Activity in Human Mammary Epithelial Cells
1994 · Zhiqiang Zou, Anthony Anisowicz, et al. · Science · 912
Implications of the three-dimensional structure of .alpha.1-antitrypsin for structure and function of serpins
1989 · R. Huber, R. W. Carrell · Biochemistry · 883
Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis
2014 · Manuel Valiente, Anna C. Obenauf, et al. · Cell · 878
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An overview of the serpin superfamily.
2006 · Ruby HP Law, Qingwei Zhang, et al. · Genome biology · 725
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The anticoagulant activation of antithrombin by heparin
1997 · Lei Jin, Jan Pieter Abrahams, et al. · Proceedings of the National Academy of Sciences · 685
Innate immune responses of a lepidopteran insect, Manduca sexta
2004 · Michael R. Kanost, Haobo Jiang, et al. · Immunological Reviews · 645
Phylogeny of the Serpin Superfamily: Implications of Patterns of Amino Acid Conservation for Structure and Function
2000 · James A. Irving, Robert N. Pike, et al. · Genome Research · 598
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Structural basis of latency in plasminogen activator inhibitor-1
1992 · James Mottonen, Arne Strand, et al. · Nature · 553
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor
1974 · Robert Huber, Dietmar Kukla, et al. · Journal of Molecular Biology · 549
Molecular basis of alpha-1-antitrypsin deficiency
1988 · Mark Brantly, Toshihiro Nukiwa, et al. · The American Journal of Medicine · 521
Sequencing of Culex quinquefasciatus Establishes a Platform for Mosquito Comparative Genomics
2010 · Peter Arensburger, Karine Megy, et al. · Science · 472
The Kallikrein-Kinin System: Current and Future Pharmacological Targets
2005 · Marie Eve Moreau, Nancy Garbacki, et al. · Journal of Pharmacological Sciences · 458
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Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family.
1993 · F R Steele, G J Chader, et al. · Proceedings of the National Academy of Sciences · 457
Maspin is an angiogenesis inhibitor
2000 · Ming Zhang, Olga Volpert, et al. · Nature Medicine · 456
REVIEW: Plasminogen Activator Inhibitor‐1 (PAI‐1): A Key Factor Linking Fibrinolysis and Age‐Related Subclinical and Clinical Conditions
2010 · Matteo Cesari, Marco Pahor, et al. · Cardiovascular Therapeutics · 449
Alpha 1 -Antitrypsin Deficiency — A Model for Conformational Diseases
2002 · Robin W. Carrell, David A. Lomas · New England Journal of Medicine · 448
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 · Elena A. Levashina, Emma Langley, et al. · Science · 436
Antiangiogenic Activity of the Cleaved Conformation of the Serpin Antithrombin
1999 · Michael S. O'Reilly, Steven Pirie-Shepherd, et al. · Science · 432
Works count: 4,296
Citation count: 134,900
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