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Keyword

Slit2

Description: A secreted protein in the SLIT family that guides cell and axon migration and is studied in developmental biology and cancer research.
OpenAlex ID: keywords/slit2
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
2012 · Martin Peifer, Lynnette Fernández-Cuesta, et al. · Nature Genetics · 1,397
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Slit Proteins Bind Robo Receptors and Have an Evolutionarily Conserved Role in Repulsive Axon Guidance
1999 · Katja Brose, Kimberly S Bland, et al. · Cell · 1,223
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Biochemical Purification of a Mammalian Slit Protein as a Positive Regulator of Sensory Axon Elongation and Branching
1999 · Kuan Hong Wang, Katja Brose, et al. · Cell · 471
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Conserved Roles for Slit and Robo Proteins in Midline Commissural Axon Guidance
2004 · Hua Long, Christelle Sabatier, et al. · Neuron · 450
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Slit1 and Slit2 Cooperate to Prevent Premature Midline Crossing of Retinal Axons in the Mouse Visual System
2002 · Andrew S. Plump, Lynda Erskine, et al. · Neuron · 440
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MiR-218 Inhibits Invasion and Metastasis of Gastric Cancer by Targeting the Robo1 Receptor
2010 · Jun Tie, Yanglin Pan, et al. · PLoS Genetics · 439
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Slit Proteins Prevent Midline Crossing and Determine the Dorsoventral Position of Major Axonal Pathways in the Mammalian Forebrain
2002 · Anil Bagri, Oscar Marı́n, et al. · Neuron · 426
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Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity
2003 · Biao Wang, Yang Xiao, et al. · Cancer Cell · 398
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SLIT2-Mediated ROBO2 Signaling Restricts Kidney Induction to a Single Site
2004 · Uta Grieshammer, Le Ma, et al. · Developmental Cell · 397
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Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability
2008 · Christopher A Jones, Nyall R London, et al. · Nature Medicine · 392
Slit2-Mediated Chemorepulsion and Collapse of Developing Forebrain Axons
1999 · Kim Tuyen Nguyen Ba-Charvet, Katja Brose, et al. · Neuron · 284
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miR-218 Suppresses Nasopharyngeal Cancer Progression through Downregulation of Survivin and the SLIT2-ROBO1 Pathway
2011 · Nehad M. Alajez, Michelle Lenarduzzi, et al. · Cancer Research · 283
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Signaling Mechanisms Underlying Slit2-Induced Collapse of Xenopus Retinal Growth Cones
2006 · Michael Piper, Richard Anderson, et al. · Neuron · 272
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Retinal Ganglion Cell Axon Guidance in the Mouse Optic Chiasm: Expression and Function of Robos and Slits
2000 · Lynda Erskine, Scott E. Williams, et al. · Journal of Neuroscience · 265
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Spatiotemporal expression patterns of slit and robo genes in the rat brain
2001 · Valérie Marillat, Oliver Cases, et al. · The Journal of Comparative Neurology · 252
Chemorepulsion of Neuronal Migration by Slit2 in the Developing Mammalian Forebrain
1999 · Huaiyu Hu · Neuron · 248
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From QTL to gene: the harvest begins
2002 · Ron Korstanje, Beverly Paigen · Nature Genetics · 242
Multiple Roles for Slits in the Control of Cell Migration in the Rostral Migratory Stream
2004 · Kim T. Nguyen-Ba-Charvet, Nathalie Picard-Riera, et al. · Journal of Neuroscience · 232
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Robo1 and Robo2 Cooperate to Control the Guidance of Major Axonal Tracts in the Mammalian Forebrain
2007 · Guillermina López-Bendito, Nuria Flames, et al. · Journal of Neuroscience · 231
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Abnormal Development of Forebrain Midline Glia and Commissural Projections inNfiaKnock-Out Mice
2003 · Tianzhi Shu, Kenneth G. Butz, et al. · Journal of Neuroscience · 217
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SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers.
2002 · Ashraf Dallol, Nancy Fernandes Da Silva, et al. · PubMed · 215
Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer’s disease
2020 · Hong Wang, Kaushik Kumar Dey, et al. · Molecular Neurodegeneration · 210
Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein
2001 · Huaiyu Hu · Nature Neuroscience · 203
Neuronal substance P drives metastasis through an extracellular RNA–TLR7 axis
2024 · Veena Padmanaban, Isabel Keller, et al. · Nature · 199
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Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization
2015 · Nicolas Rama, Alexandre Dubrac, et al. · Nature Medicine · 198
Works count: 1,234
Citation count: 31,920
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