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Keyword

Smad2

Description: A protein encoded by the human SMAD2 gene that transmits transforming growth factor beta signals and regulates cellular processes.
Wikidata ID: wiki/Q14903945
OpenAlex ID: keywords/smad2
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 · Carl-Henrik Heldin, Kohei Miyazono, et al. · Nature · 3,697
Transcriptional control by the TGF‐β/Smad signaling system
2000 · Joan Massagué, David Wotton · The EMBO Journal · 1,967
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
1997 · Atsuhito Nakao, Mozhgan Afrakhte, et al. · Nature · 1,809
Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene
1998 · Sylviane Dennler, Susumu Itoh, et al. · The EMBO Journal · 1,793
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The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling
1997 · Hidetoshi Hayashi, Shirin Abdollah, et al. · Cell · 1,334
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New insights into TGF-β/Smad signaling in tissue fibrosis
2018 · He-He Hu, Dan-Qian Chen, et al. · Chemico-Biological Interactions · 1,183
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Distinct endocytic pathways regulate TGF-β receptor signalling and turnover
2003 · Gianni M. Di Guglielmo, Christine Le Roy, et al. · Nature Cell Biology · 1,152
Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors
2002 · Marie‐José Goumans, Gudrun Valdimarsdottir, et al. · The EMBO Journal · 1,125
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TGF‐β receptor‐mediated signalling through Smad2, Smad3 and Smad4
1997 · Atsuhito Nakao, Takeshi Imamura, et al. · The EMBO Journal · 1,070
A mechanism of repression of TGFbeta / Smad signaling by oncogenic Ras
1999 · M. Kretzschmar, J. Doody, et al. · Genes & Development · 1,004
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SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor
1998 · Tomoo Tsukazaki, Theodore A Chiang, et al. · Cell · 968
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De novo mutations in histone-modifying genes in congenital heart disease
2013 · Samir Zaidi, Murim Choi, et al. · Nature · 935
Smad regulation in TGF-β signal transduction
2001 · Aristidis Moustakas, Serhiy Souchelnytskyi, et al. · Journal of Cell Science · 929
Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways
1996 · Giorgio Lagna, Akiko Hata, et al. · Nature · 905
Fibroblast-specific TGF-β–Smad2/3 signaling underlies cardiac fibrosis
2017 · Hadi Khalil, Onur Kanisicak, et al. · Journal of Clinical Investigation · 899
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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation
1999 · Haitao Zhu, Peter Kavsak, et al. · Nature · 846
Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size
2009 · Anne Ulrike Trendelenburg, Angelika Meyer, et al. · American Journal of Physiology-Cell Physiology · 790
TGF-β/SMAD Pathway and Its Regulation in Hepatic Fibrosis
2016 · Fengyun Xu, Changwei Liu, et al. · Journal of Histochemistry & Cytochemistry · 756
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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
2005 · Jae-Hyuck Shim, Changchun Xiao, et al. · Genes & Development · 738
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The EGF-CFC Protein One-Eyed Pinhead Is Essential for Nodal Signaling
1999 · Kira Gritsman, Jiaojiao Zhang, et al. · Cell · 713
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Smad3 Mutant Mice Develop Metastatic Colorectal Cancer
1998 · Yuan Zhu, James A Richardson, et al. · Cell · 671
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TGF-β/Smad signaling in renal fibrosis
2015 · Xiao-Ming Meng, Patrick Ming-Kuen Tang, et al. · Frontiers in Physiology · 666
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Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation
2011 · Hui Yao Lan · International Journal of Biological Sciences · 652
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Nodal Signaling in Vertebrate Development
2003 · Alexander F. Schier · Annual Review of Cell and Developmental Biology · 634
TGF-β1 Plays an Important Role in the Mechanism of CD4+CD25+ Regulatory T Cell Activity in Both Humans and Mice
2004 · Kazuhiko Nakamura, Atsushi Kitani, et al. · The Journal of Immunology · 630
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Works count: 4,785
Citation count: 183,300
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