Keyword

solid dispersion

Description: A pharmaceutical formulation in which one or more active substances are dispersed in a solid carrier to improve properties such as dissolution.

Primary topic: Drug Solubulity and Delivery Systems (79%)

Wikidata ID: wiki/Q10925824

OpenAlex ID: keywords/solid-dispersion

Improving drug solubility for oral delivery using solid dispersions

2000 · C Leuner · European Journal of Pharmaceutics and Biopharmaceutics · 2,576

Drug Solubility: Importance and Enhancement Techniques

2012 · Ketan T. Savjani, Anuradha K. Gajjar, et al. · ISRN Pharmaceutics · 2,009

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Pharmaceutical Applications of Solid Dispersion Systems

1971 · Win Loung Chiou, Sidney Riegelman · Journal of Pharmaceutical Sciences · 1,799

Solid dispersion of poorly water‐soluble drugs: Early promises, subsequent problems, and recent breakthroughs

1999 · Abu T.M. Serajuddin · Journal of Pharmaceutical Sciences · 1,649

Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs

2007 · Teófilo Vasconcelos, Bruno Sarmento, et al. · Drug Discovery Today · 1,566

The mechanisms of drug release from solid dispersions in water-soluble polymers

2002 · Duncan Q.M Craig · International Journal of Pharmaceutics · 936

Curcumin nanoformulations: A review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment

2014 · Ornchuma Naksuriya, Siriporn Okonogi, et al. · Biomaterials · 841

Pharmaceutical Applications of Hot-Melt Extrusion: Part I

2007 · Michael M. Crowley, Feng Zhang, et al. · Drug Development and Industrial Pharmacy · 825

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Melt extrusion: from process to drug delivery technology

2002 · Jörg Breitenbach · European Journal of Pharmaceutics and Biopharmaceutics · 742

Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics

2022 · Arvind Kumar Singh Chandel, Dixit Bhalani, et al. · Biomedicines · 707

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Solubility parameters as predictors of miscibility in solid dispersions

1999 · David J. Greenhalgh, Adrian C. Williams, et al. · Journal of Pharmaceutical Sciences · 674

Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs

2013 · Chau Le-Ngoc Vo, Chulhun Park, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 652

Fundamental aspects of solid dispersion technology for poorly soluble drugs

2013 · Yanbin Huang, Wei-Guo Dai · Acta Pharmaceutica Sinica B · 596

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Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation

2015 · Hemlata Patil, Roshan V. Tiwari, et al. · AAPS PharmSciTech · 584

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Review: physical chemistry of solid dispersions

2009 · Sandrien Janssens, Guy Van den Mooter · Journal of Pharmacy and Pharmacology · 580

Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: Formulation and process considerations

2012 · Amrit Paudel, Zelalem Ayenew Worku, et al. · International Journal of Pharmaceutics · 560

The applications of Vitamin E TPGS in drug delivery

2013 · Yuanyuan Guo, Jun Luo, et al. · European Journal of Pharmaceutical Sciences · 523

The current status of solid dispersions.

1986 · J L Ford · PubMed · 469

Recent advances in co-amorphous drug formulations

2016 · Swapnil Jayant Dengale, Holger Grohganz, et al. · Advanced Drug Delivery Reviews · 462

Solid dispersion of carbamazepine in PVP K30 by conventional solvent evaporation and supercritical methods

2004 · S Sethia, E Squillante · International Journal of Pharmaceutics · 442

Physical stabilisation of amorphous ketoconazole in solid dispersions with polyvinylpyrrolidone K25

2001 · G. Van den Mooter, M. Wuyts, et al. · European Journal of Pharmaceutical Sciences · 429

Studies on dissolution enhancement and mathematical modeling of drug release of a poorly water-soluble drug using water-soluble carriers

2006 · Naveen Ahuja, Om Prakash Katare, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 388

Influence of Different Polymers on the Crystallization Tendency of Molecularly Dispersed Amorphous Felodipine

2006 · Hajime Konno, Lynne S. Taylor · Journal of Pharmaceutical Sciences · 384

Surface Chemistry of Surfactants and Polymers

2014 · Bengt Kronberg, Krister Holmberg, et al. · Wiley eBooks · 383

Antiviral effect of phytochemicals from medicinal plants: Applications and drug delivery strategies

2019 · Shimon Ben-Shabat, Ludmila Yarmolinsky, et al. · Drug Delivery and Translational Research · 360

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Works count: 9,450

Citation count: 154,300