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SRY
Description:
SRY is the Y-chromosome gene encoding a transcription factor that initiates testis development and male sex determination in mammals.
Primary topic:
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities (56%)
Related topic:
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities (56%)
Wikidata ID:
wiki/Q14819281
OpenAlex ID:
keywords/sry
Natural RNA circles function as efficient microRNA sponges
2013
·
Thomas B. Hansen
, Trine I. Jensen
, et al.
·
Nature
·
7,976
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
2013
·
Haoyi Wang
, Hui Yang
, et al.
·
Cell
·
3,491
PDF
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer
2008
·
Ryohei Sekido
, Robin Lovell-Badge
·
Nature
·
969
Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation
2009
·
N. Henriette Uhlenhaut
, Susanne Jakob
, et al.
·
Cell
·
962
PDF
Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds
1996
·
Sara Morais da Silva
, Adam Hacker
, et al.
·
Nature Genetics
·
795
A male-specific role for SOX9 in vertebrate sex determination
1996
·
Jill Kent
, Susan C. Wheatley
, et al.
·
Development
·
710
Sertoli cell signaling by Desert hedgehog regulates the male germline
1996
·
Mark J Bitgood
, Liya Shen
, et al.
·
Current Biology
·
688
PDF
Sox9 induces testis development in XX transgenic mice
2001
·
Valerie P.I. Vidal
, Marie-Christine Chaboissier
, et al.
·
Nature Genetics
·
679
The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures
1992
·
Klaus Giese
, Jeffery Cox
, et al.
·
Cell
·
676
Male-to-Female Sex Reversal in Mice Lacking Fibroblast Growth Factor 9
2001
·
Jennifer S. Colvin
, Rebecca P. Green
, et al.
·
Cell
·
589
PDF
Fgf9 and Wnt4 Act as Antagonistic Signals to Regulate Mammalian Sex Determination
2006
·
Yuna Kim
, Akio Kobayashi
, et al.
·
PLoS Biology
·
574
PDF
Functional analysis of Sox8 and Sox9 during sex determination in the mouse
2004
·
Marie-Christine Chaboissier
, Akio Kobayashi
, et al.
·
Development
·
558
PDF
Dax1 antagonizes Sry action in mammalian sex determination
1998
·
Amanda Swain
, Veronica Narvaez
, et al.
·
Nature
·
550
One tissue, two fates: molecular genetic events that underlie testis versus ovary development
2004
·
Jennifer Brennan
, Blanche Capel
·
Nature Reviews Genetics
·
549
Two Splice Variants of the Wilms' Tumor 1 Gene Have Distinct Functions during Sex Determination and Nephron Formation
2001
·
Annette Hammes
, Jian-Kan Guo
, et al.
·
Cell
·
541
PDF
Identification and cloning of TCF‐1, a T lymphocyte‐specific transcription factor containing a sequence‐specific HMG box.
1991
·
M. van de Wetering
, M. Oosterwegel
, et al.
·
The EMBO Journal
·
538
Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis
2002
·
Humphrey Hung-Chang Yao
, Wendy Whoriskey
, et al.
·
Genes & Development
·
537
PDF
Origins and functional evolution of Y chromosomes across mammals
2014
·
Diego Cortez
, Ray Marin
, et al.
·
Nature
·
532
A Model System for Study of Sex Chromosome Effects on Sexually Dimorphic Neural and Behavioral Traits
2002
·
Geert J. De Vries
, Emilie F. Rissman
, et al.
·
Journal of Neuroscience
·
510
PDF
A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2
1996
·
Jérôme Collignon
, Shanthini Sockanathan
, et al.
·
Development
·
496
Expression of Dmrt1 in the Genital Ridge of Mouse and Chicken Embryos Suggests a Role in Vertebrate Sexual Development
1999
·
Christopher S. Raymond
, Jae R. Kettlewell
, et al.
·
Developmental Biology
·
491
PDF
Sox genes find their feet
1997
·
Larysa H Pevny
, Robin Lovell-Badge
·
Current Opinion in Genetics & Development
·
486
Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors
2007
·
Véronique Lefebvre
, Bogdan Dumitriu
, et al.
·
The International Journal of Biochemistry & Cell Biology
·
467
Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex
1995
·
Milton H Werner
, Jeffrey R Huth
, et al.
·
Cell
·
465
PDF
Sertoli Cells of the Mouse Testis Originate from the Coelomic Epithelium
1998
·
Jeannie Karl
, Blanche Capel
·
Developmental Biology
·
462
PDF
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Works count:
1,667
Citation count:
83,150
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