Keyword

STAT5

Description: A family of signal transducer and activator of transcription proteins involved in cytokine and growth-factor signaling and gene regulation.

Primary topic: Cytokine Signaling Pathways and Interactions (23%)

Wikidata ID: wiki/Q4210018

OpenAlex ID: keywords/stat5

STATs in cancer inflammation and immunity: a leading role for STAT3

2009 · Hua Yu, Drew Pardoll, et al. · Nature reviews. Cancer · 4,370

The STATs of cancer — new molecular targets come of age

2004 · Hua Yu, Richard Jove · Nature reviews. Cancer · 2,279

TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway

1995 · C. Schindler, J. E. Darnell · Annual Review of Biochemistry · 1,810

STATs in oncogenesis

2000 · Tammy Bowman, Roy Garcia, et al. · Oncogene · 1,743

Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation

2007 · Arian Laurence, Cristina M. Tato, et al. · Immunity · 1,505

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The role of STATs in transcriptional control and their impact on cellular function

2000 · Jacqueline Bromberg, James E Darnell · Oncogene · 1,203

Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention.

2002 · Ralf Buettner, Linda B Mora, et al. · PubMed · 1,024

Signaling and Function of Interleukin-2 in T Lymphocytes

2018 · Sarah H. Ross, Doreen A. Cantrell · Annual Review of Immunology · 976

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

2012 · Christina E. Zielinski, Federico Mele, et al. · Nature · 921

An essential role for the IL-2 receptor in Treg cell function

2016 · Takatoshi Chinen, Arun K Kannan, et al. · Nature Immunology · 890

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

2011 · Thordur Oskarsson, Swarnali Acharyya, et al. · Nature Medicine · 869

IL-2 Receptor β-Dependent STAT5 Activation Is Required for the Development of Foxp3+ Regulatory T Cells

2007 · Matthew A Burchill, Jianying Yang, et al. · The Journal of Immunology · 835

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Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

2010 · Matthew E. Pipkin, Jilian A. Sacks, et al. · Immunity · 796

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Defective STAT signaling by the leptin receptor in diabetic mice.

1996 · N Ghilardi, S Ziegler, et al. · Proceedings of the National Academy of Sciences · 793

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

2009 · Li-Fan Lu, To-Ha Thai, et al. · Immunity · 783

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Stat proteins and oncogenesis

2002 · Jacqueline Bromberg · Journal of Clinical Investigation · 771

Phosphotyrosine interactome of the ErbB‐receptor kinase family

2005 · Waltraud X Schulze, Lei Deng, et al. · Molecular Systems Biology · 751

The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15

1995 · Jian-Xin Lin, Thi-Sau Migone, et al. · Immunity · 751

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IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

2006 · Emmanuel Zorn, Erik A. Nelson, et al. · Blood · 740

Fetal Anemia and Apoptosis of Red Cell Progenitors in Stat5a−/−5b−/− Mice

1999 · Merav Socolovsky, Amy E.J Fallon, et al. · Cell · 696

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Myeloid Suppressor Lines Inhibit T Cell Responses by an NO-Dependent Mechanism

2002 · Alessandra Mazzoni, Vincenzo Bronte, et al. · The Journal of Immunology · 691

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Stat proteins and oncogenesis

2002 · Jacqueline Bromberg · Journal of Clinical Investigation · 681

Ineffective erythropoiesis in Stat5a−/−5b−/− mice due to decreased survival of early erythroblasts

2001 · Merav Socolovsky, Hyung-song Nam, et al. · Blood · 681

Functional interactions between Stat5 and the glucocorticoid receptor

1996 · Elisabeth Stöcklin, Manuela Wissler, et al. · Nature · 678

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BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571

2002 · Nicholas J. Donato, Ji Yuan Wu, et al. · Blood · 663

Works count: 6,213

Citation count: 236,200