Keyword

STAT5B

Description: STAT5B is a protein-coding gene whose product is a transcription factor involved in cytokine signaling, cell growth, and immune regulation.

Primary topic: Cytokine Signaling Pathways and Interactions (25%)

Wikidata ID: wiki/Q18031752

OpenAlex ID: keywords/stat5b

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

1998 · Stephan Teglund, Catriona McKay, et al. · Cell · 1,267

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Stat5a is mandatory for adult mammary gland development and lactogenesis.

1997 · X Liu, G W Robinson, et al. · Genes & Development · 1,112

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

1997 · Garry B. Udy, Raewyn P. Towers, et al. · Proceedings of the National Academy of Sciences · 988

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

2009 · David J. Waxman, Minita G. Holloway · Molecular Pharmacology · 816

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Fetal Anemia and Apoptosis of Red Cell Progenitors in Stat5a−/−5b−/− Mice

1999 · Merav Socolovsky, Amy E.J Fallon, et al. · Cell · 696

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Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.

1995 · X Liu, G W Robinson, et al. · Proceedings of the National Academy of Sciences · 557

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Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells

1999 · Richard Moriggl, David J Topham, et al. · Immunity · 547

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Growth Hormone Insensitivity Associated with a STAT5b Mutation

2003 · Eric M. Kofoed, Vivian Hwa, et al. · New England Journal of Medicine · 525

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SOCS-3 Is an Insulin-induced Negative Regulator of Insulin Signaling

2000 · Brice Emanuelli, Pascal Peraldi, et al. · Journal of Biological Chemistry · 468

Growth Hormone Regulation of Sex-Dependent Liver Gene Expression

2006 · David J. Waxman, Caitlin O’Connor · Molecular Endocrinology · 460

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The potential and controversy of targeting STAT family members in cancer

2019 · Yannick Verhoeven, Sam Tilborghs, et al. · Seminars in Cancer Biology · 407

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Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells

2015 · Can Küçük, Bei Jiang, et al. · Nature Communications · 394

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DNA Binding Specificity of Different STAT Proteins

2001 · Georg B. Ehret, Patrick Reichenbach, et al. · Journal of Biological Chemistry · 370

The role of Stat5a and Stat5b in signaling by IL-2 family cytokines

2000 · Jian-Xin Lin, Warren J Leonard · Oncogene · 368

Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma

2015 · Lu Jiang, Zhao-Hui Gu, et al. · Nature Genetics · 366

SOCS/CIS Protein Inhibition of Growth Hormone-stimulated STAT5 Signaling by Multiple Mechanisms

1999 · Prabha A. Ram, David J. Waxman · Journal of Biological Chemistry · 362

Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B

2008 · Lothar Hennighausen, Gertraud W. Robinson · Genes & Development · 356

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Functional Roles of STAT Family Proteins: Lessons from Knockout Mice

1999 · Shizuo Akira · Stem Cells · 349

Stat5b Is Essential for Natural Killer Cell–mediated Proliferation and Cytolytic Activity

1998 · Kazunori Imada, Eda T. Bloom, et al. · The Journal of Experimental Medicine · 325

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Inborn Errors of Human JAKs and STATs

2012 · Jean-Laurent Casanova, Steven M. Holland, et al. · Immunity · 320

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STAT family of transcription factors in cytokine-mediated biological responses

2000 · Kiyoshi Takeda, Shizuo Akira · Cytokine & Growth Factor Reviews · 310

LGL leukemia: from pathogenesis to treatment

2017 · Thierry Lamy, Aline Moignet, et al. · Blood · 304

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Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

2013 · Hanna L. M. Rajala, Samuli Eldfors, et al. · Blood · 294

Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks

2009 · Rachel Yehuda, Guiqing Cai, et al. · Biological Psychiatry · 294

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miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity

2015 · Keith O’Brien, Michelle C. Lowry, et al. · Oncotarget · 273

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Works count: 1,667

Citation count: 54,140