Keyword

statins

Description: A class of medicines that lower blood cholesterol by inhibiting an enzyme involved in cholesterol synthesis, often used to reduce cardiovascular risk.

Primary topic: Lipoproteins and Cardiovascular Health (34%)

Wikidata ID: wiki/Q954845

OpenAlex ID: keywords/statins

Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)

2001 · Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults · JAMA · 26,038

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1994 · Anders Olsson, John J.V. McMurray, et al. · The Lancet · 8,467

Inflammation and Atherosclerosis

2002 · Peter Libby, Paul M. Ridker, et al. · Circulation · 7,709

Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia

1995 · James Shepherd, Stuart M. Cobbe, et al. · New England Journal of Medicine · 7,464

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The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels

1996 · Frank M. Sacks, Marc A. Pfeffer, et al. · New England Journal of Medicine · 7,448

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2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults

2013 · Neil J. Stone, Jennifer G. Robinson, et al. · Circulation · 7,089

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial

2002 · The Lancet · 7,016

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins

2005 · ‡ · The Lancet · 6,857

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

2019 · Scott M. Grundy, Neil J. Stone, et al. · Circulation · 6,187

Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels

1998 · John R. Downs, Michael Clearfield, et al. · JAMA · 5,252

Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes

2004 · Christopher P. Cannon, Eugene Braunwald, et al. · New England Journal of Medicine · 4,948

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2013 ESC guidelines on the management of stable coronary artery disease

2013 · Task Force Members, Gilles Montalescot, et al. · European Heart Journal · 4,524

Nitric oxide synthases: regulation and function

2011 · U. Forstermann, W. C. Sessa · European Heart Journal · 4,398

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2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults

2013 · Neil J. Stone, Jennifer G. Robinson, et al. · Journal of the American College of Cardiology · 3,846

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial

2003 · Peter S Sever, Björn Dahlöf, et al. · The Lancet · 3,782

Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial

2004 · Helen M Colhoun, D John Betteridge, et al. · The Lancet · 3,765

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1994 · SCANDINAVIANSIMVASTATINSURVIVAL · The Lancet · 3,645

Prevention of Coronary Heart Disease With Pravastatin in Men With Hypercholesterolemia

1995 · J Ames S Hepherd, S Tuart M. C Obbe, et al. · 3,453

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

2002 · James Shepherd, Gerard J Blauw, et al. · The Lancet · 3,388

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

2005 · ‡ · The Lancet · 3,300

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

2004 · T.R. PEDERSEN · Atherosclerosis Supplements · 3,106

Management of Hyperglycemia in Type 2 Diabetes, 2015: A Patient-Centered Approach: Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes

2014 · Silvio E. Inzucchi, Richard M. Bergenstal, et al. · Diabetes Care · 3,069

Atherosclerosis

2001 · Christopher K. Glass, Joseph L. Witztum · Cell · 3,066

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Broadening horizons: the role of ferroptosis in cancer

2021 · Xin Chen, Rui Kang, et al. · Nature Reviews Clinical Oncology · 2,905

MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial

2003 · Rory Collins, Jane Armitage, et al. · The Lancet · 2,889

Works count: 99,240

Citation count: 1,917,000