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Keyword

SVCT2

Description: A sodium-dependent vitamin C transporter protein encoded by SLC23A2, involved in cellular uptake and transport of ascorbate.
Wikidata ID: wiki/Q18034917
OpenAlex ID: keywords/svct2
A family of mammalian Na+-dependent L-ascorbic acid transporters
1999 · Hiroyasu Tsukaguchi, Taro Tokui, et al. · Nature · 883
Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2
2009 · Fiona E. Harrison, James M. May · Free Radical Biology and Medicine · 660
Regulation of Vitamin C Transport
2005 · John X. Wilson · Annual Review of Nutrition · 377
Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival
2002 · Sotiria Sotiriou, Suzana Gispert, et al. · Nature Medicine · 365
SVCT1 and SVCT2: key proteins for vitamin C uptake
2007 · I. Savini, A. Rossi, et al. · Amino Acids · 358
Vitamin C in Health and Disease: Its Role in the Metabolism of Cells and Redox State in the Brain
2015 · Rodrigo Figueroa-Méndez, Selva Rivas-Arancibia · Frontiers in Physiology · 258
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Vitamin C transport systems of mammalian cells
2001 · Wei-Jun Liang, Daniel Johnson, et al. · Molecular Membrane Biology · 256
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Human Vitamin C (l-Ascorbic Acid) Transporter SVCT1
2000 · Yangxi Wang, Bryan Mackenzie, et al. · Biochemical and Biophysical Research Communications · 216
Vitamin C Transport and Its Role in the Central Nervous System
2011 · James M. May · Sub-cellular biochemistry/Subcellular biochemistry · 186
Vitamin C preferentially kills cancer stem cells in hepatocellular carcinoma via SVCT-2
2018 · Hongwei Lv, Changzheng Wang, et al. · npj Precision Oncology · 170
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Human Placental Sodium-Dependent Vitamin C Transporter (SVCT2): Molecular Cloning and Transport Function
1999 · D.Prasanna Rajan, Wei Huang, et al. · Biochemical and Biophysical Research Communications · 163
Sodium-dependent ascorbic acid transporter family SLC23
2004 · Hitomi Takanaga, Bryan Mackenzie, et al. · Pflügers Archiv - European Journal of Physiology · 161
The sodium-dependent ascorbic acid transporter family SLC23
2013 · Marc Bürzle, Yoshiro Suzuki, et al. · Molecular Aspects of Medicine · 157
Vitamin C Deficiency in the Brain Impairs Cognition, Increases Amyloid Accumulation and Deposition, and Oxidative Stress in APP/PSEN1 and Normally Aging Mice
2015 · Shilpy Dixit, Alexandra Bernardo, et al. · ACS Chemical Neuroscience · 135
Ascorbate transport by primary cultured neurons and its role in neuronal function and protection against excitotoxicity
2007 · Shenfeng Qiu, Liying Li, et al. · Journal of Neuroscience Research · 133
Vitamin C transporters
2008 · C. I. Rivas, F. A. Zúñiga, et al. · Journal of Physiology and Biochemistry · 127
Vitamin C Facilitates Dopamine Neuron Differentiation in Fetal Midbrain Through TET1- and JMJD3-Dependent Epigenetic Control Manner
2014 · Xi-Biao He, Mirang Kim, et al. · Stem Cells · 119
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High‐affinity sodium–vitamin C co‐transporters (SVCT) expression in embryonic mouse neurons
2001 · Maite Castro, Teresa Caprile, et al. · Journal of Neurochemistry · 116
A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington’s disease in mice
2013 · Aníbal I. Acuña, Magdalena Esparza, et al. · Nature Communications · 115
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Polarized localization of vitamin C transporters, SVCT1 and SVCT2, in epithelial cells
2005 · James C. Boyer, Christine E. Campbell, et al. · Biochemical and Biophysical Research Communications · 114
Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model
2006 · Xingjun Fan, Lixing W. Reneker, et al. · Proceedings of the National Academy of Sciences · 113
Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts
2012 · Yuki Kishimoto, Norikatsu Saito, et al. · Biochemical and Biophysical Research Communications · 110
Up-regulation and Polarized Expression of the Sodium-Ascorbic Acid Transporter SVCT1 in Post-confluent Differentiated CaCo-2 Cells
2003 · Nancy P. Maulén, Esther A. Henrı́quez, et al. · Journal of Biological Chemistry · 110
The SLC23 family of ascorbate transporters: ensuring that you get and keep your daily dose of vitamin C
2011 · James M May · British Journal of Pharmacology · 107
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Mechanistic Insights and Functional Determinants of the Transport Cycle of the Ascorbic Acid Transporter SVCT2
2006 · Alejandro Godoy, Valeska Ormazabal, et al. · Journal of Biological Chemistry · 107
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Works count: 423
Citation count: 12,400
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