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Keyword

TCF4

Description: A human protein-coding gene whose product is a transcription factor involved in Wnt signaling and regulation of gene expression.
Wikidata ID: wiki/Q14913982
OpenAlex ID: keywords/tcf4
Identification of c- MYC as a Target of the APC Pathway
1998 · Tong-Chuan He, Andrew B. Sparks, et al. · Science · 4,565
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
1997 · Patrice J. Morin, Andrew B. Sparks, et al. · Science · 3,981
Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC −/− Colon Carcinoma
1997 · Vladimir Korinek, Nick Barker, et al. · Science · 3,304
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The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells
2002 · Marc van de Wetering, Elena Sancho, et al. · Cell · 2,029
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Inhibition of Adipogenesis by Wnt Signaling
2000 · Sarah E. Ross, Nahid Hemati, et al. · Science · 1,875
Common variants conferring risk of schizophrenia
2009 · †Genetic Risk and Outcome in Psychosis (GROUP), Hreinn Stefansson, et al. · Nature · 1,682
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Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
1998 · Vladimir Korinek, Nick Barker, et al. · Nature Genetics · 1,581
Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration
2011 · Malea M. Murphy, Jennifer A. Lawson, et al. · Development · 1,248
Integrative functional genomic analysis of human brain development and neuropsychiatric risks
2018 · Mingfeng Li, Gabriel Santpere, et al. · Science · 806
Vitamin D3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling
2001 · Héctor G. Pálmer, José Manuel González-Sancho, et al. · The Journal of Cell Biology · 802
β-Catenin Regulates the Expression of the Matrix Metalloproteinase-7 in Human Colorectal Cancer
1999 · Thomas Brabletz, Andreas Jung, et al. · American Journal Of Pathology · 671
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Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5
2008 · Andrea Taddei, Costanza Giampietro, et al. · Nature Cell Biology · 654
Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex
2004 · Maina Lepourcelet, Ying-Nan P. Chen, et al. · Cancer Cell · 653
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Wnt signalling induces maturation of Paneth cells in intestinal crypts
2005 · Johan H. van Es, Philippe Jay, et al. · Nature Cell Biology · 650
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
2009 · Stephen P.J. Fancy, Sergio E. Baranzini, et al. · Genes & Development · 646
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Myc deletion rescues Apc deficiency in the small intestine
2007 · Owen J. Sansom, Valerie S. Meniel, et al. · Nature · 614
Colorectal cancer and genetic alterations in the Wnt pathway
2006 · S Segditsas, I Tomlinson · Oncogene · 591
Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries
2012 · Michael E. Talkowski, Jill A. Rosenfeld, et al. · Cell · 577
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HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction
2009 · Feng Ye, Ying Chen, et al. · Nature Neuroscience · 557
Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia
2007 · Abderrahmane Kaidi, Ann Caroline Williams, et al. · Nature Cell Biology · 517
Expression of CD44 in Apc and TcfMutant Mice Implies Regulation by the WNT Pathway
1999 · Vera J.M. Wielenga, Ron Smits, et al. · American Journal Of Pathology · 512
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The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
2009 · Sari Tuupanen, Mikko Turunen, et al. · Nature Genetics · 504
The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/β-catenin signaling
2017 · Peng Han, Jing-wen Li, et al. · Molecular Cancer · 496
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Genome-wide Prediction of Mammalian Enhancers Based on Analysis of Transcription-Factor Binding Affinity
2006 · Outi Hallikas, Kimmo Palin, et al. · Cell · 472
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Wnt3a-/--like phenotype and limb deficiency in Lef1-/-Tcf1-/- mice
1999 · J. Galceran, I. Farinas, et al. · Genes & Development · 462
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Works count: 2,874
Citation count: 111,700
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