Keyword

TEAD

Description: A family of transcription factors that interact with YAP and TAZ in the Hippo signaling pathway and regulate gene expression.

Primary topic: Hippo pathway signaling and YAP/TAZ (67%)

OpenAlex ID: keywords/tead

Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance

2017 · Sydney M. Shaffer, Margaret C. Dunagin, et al. · Nature · 1,212

YAP/TAZ and ATF4 drive resistance to Sorafenib in hepatocellular carcinoma by preventing ferroptosis

2021 · Ruize Gao, Ravi K R Kalathur, et al. · EMBO Molecular Medicine · 485

Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells

2017 · J Feng, H Yang, et al. · Oncogene · 416

The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ

2018 · Lei Chang, Luca Azzolin, et al. · Nature · 328

The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1

2018 · Helena J. Janse van Rensburg, Taha Azad, et al. · Cancer Research · 306

Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets

2022 · Fanying Tang, Duo Xu, et al. · Science · 268

Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer

2018 · Jie Shen, Beibei Cao, et al. · Journal of Experimental & Clinical Cancer Research · 229

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Verteporfin suppresses cell survival, angiogenesis and vasculogenic mimicry of pancreatic ductal adenocarcinoma via disrupting the YAP ‐ TEAD complex

2016 · Honglong Wei, Fuhai Wang, et al. · Cancer Science · 219

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Snail/Slug binding interactions with YAP/TAZ control skeletal stem cell self-renewal and differentiation

2016 · Yi Tang, Tamar Feinberg, et al. · Nature Cell Biology · 211

The transcriptional co-activator TAZ interacts differentially with transcriptional enhancer factor-1 (TEF-1) family members

2005 · William M. MAHONEY, Jeong-Ho HONG, et al. · Biochemical Journal · 210

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The Role of Hippo Pathway in Cancer Stem Cell Biology.

2018 · Jae Hyung Park, Ji Eun Shin, et al. · PubMed · 194

Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

2021 · Joel D. Pearson, Katherine Huang, et al. · Cancer Cell · 175

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Skeletal cell YAP and TAZ combinatorially promote bone development

2018 · Christopher D. Kegelman, Devon E. Mason, et al. · The FASEB Journal · 175

YAP/TEAD–Mediated Transcription Controls Cellular Senescence

2013 · Qi Xie, Jing Chen, et al. · Cancer Research · 168

SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity

2018 · Fan Yao, Zhicheng Zhou, et al. · Nature Communications · 165

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The Evolutionary History of YAP and the Hippo/YAP Pathway

2011 · D. Hilman, U. Gat · Molecular Biology and Evolution · 165

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Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis

2019 · Lina Fu, Yuqiong Hu, et al. · PLoS Biology · 164

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Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development

2006 · Esther E. Creemers, Lillian B. Sutherland, et al. · Development · 146

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Targeting Hippo pathway by specific interruption of YAP‐TEAD interaction using cyclic YAP‐like peptides

2014 · Zheng Zhou, Taishan Hu, et al. · The FASEB Journal · 145

Pharmacological blockade of TEAD–YAP reveals its therapeutic limitation in cancer cells

2022 · Yang Sun, Lu Hu, et al. · Nature Communications · 141

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Epiblast Formation by TEAD-YAP-Dependent Expression of Pluripotency Factors and Competitive Elimination of Unspecified Cells

2019 · Masakazu Hashimoto, Hiroshi Sasaki · Developmental Cell · 140

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Verteporfin, a suppressor of YAP–TEAD complex, presents promising antitumor properties on ovarian cancer

2016 · Zhengyu Li, Juntao Feng, et al. · OncoTargets and Therapy · 138

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Quercetin inhibited mesangial cell proliferation of early diabetic nephropathy through the Hippo pathway

2019 · Du Lei, Li Chengcheng, et al. · Pharmacological Research · 131

Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export

2018 · Nil Ege, Anna M. Dowbaj, et al. · Cell Systems · 131

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Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain

2006 · Asokan Anbanandam, Diana C. Albarado, et al. · Proceedings of the National Academy of Sciences · 131

Works count: 579

Citation count: 13,260