Get started
Keyword

TFEB

Description: TFEB is a gene encoding a transcription factor that regulates cellular processes including autophagy and lysosomal function in human biology.
Wikidata ID: wiki/Q18032677
OpenAlex ID: keywords/tfeb
TFEB Links Autophagy to Lysosomal Biogenesis
2011 · Carmine Settembre, Chiara Di Malta, et al. · Science · 3,341
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 · Marco Sardiello, Michela Palmieri, et al. · Science · 2,531
A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
2012 · Carmine Settembre, Roberto Zoncu, et al. · The EMBO Journal · 1,955
PDF
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 · Carmine Settembre, Alessandro Fraldi, et al. · Nature Reviews Molecular Cell Biology · 1,700
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
2015 · Diego L. Medina, Simone Di Paola, et al. · Nature Cell Biology · 1,414
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
2012 · Jose A. Martina, Yong Chen, et al. · Autophagy · 1,367
PDF
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
2012 · Agnes Roczniak-Ferguson, Constance S. Petit, et al. · Science Signaling · 1,366
MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease
2014 · L Kordelas, V Rebmann, et al. · Leukemia · 1,085
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
2013 · Carmine Settembre, Rossella De Cegli, et al. · Nature Cell Biology · 1,017
Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
2011 · Michela Palmieri, Soren Impey, et al. · Human Molecular Genetics · 1,017
A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation
2019 · Alexandra Grubman, Gabriel Chew, et al. · Nature Neuroscience · 948
TFEB at a glance
2016 · Gennaro Napolitano, Andrea Ballabio · Journal of Cell Science · 853
Pathogenic Lysosomal Depletion in Parkinson's Disease
2010 · Benjamin Dehay, Jordi Bové, et al. · Journal of Neuroscience · 824
PDF
Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
2015 · Rushika M. Perera, Svetlana Stoykova, et al. · Nature · 796
PDF
The lysosome: from waste bag to potential therapeutic target
2013 · Hanna Appelqvist, Petra Wäster, et al. · Journal of Molecular Cell Biology · 769
PDF
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
2013 · Mickael Decressac, Bengt Mattsson, et al. · Proceedings of the National Academy of Sciences · 751
Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance
2011 · Diego L. Medina, Alessandro Fraldi, et al. · Developmental Cell · 717
PDF
microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family.
1994 · T J Hemesath, E Steingrímsson, et al. · Genes & Development · 673
PDF
Regulation of mTORC1 and its impact on gene expression at a glance
2013 · Mathieu Laplante, David M. Sabatini · Journal of Cell Science · 667
MCOLN1 is a ROS sensor in lysosomes that regulates autophagy
2016 · Xiaoli Zhang, Xiping Cheng, et al. · Nature Communications · 557
PDF
The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans
2013 · Louis R. Lapierre, C. Daniel De Magalhaes Filho, et al. · Nature Communications · 544
PDF
The complex relationship between TFEB transcription factor phosphorylation and subcellular localization
2018 · Rosa Puertollano, Shawn M Ferguson, et al. · The EMBO Journal · 531
PDF
METTL3 and ALKBH5 oppositely regulate m 6 A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes
2019 · Huiwen Song, Xing Feng, et al. · Autophagy · 517
Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype
2018 · Degao Chen, Jing Xie, et al. · Nature Communications · 489
PDF
Lysosomes as mediators of drug resistance in cancer
2015 · Benny Zhitomirsky, Yehuda G. Assaraf · Drug Resistance Updates · 482
Works count: 3,743
Citation count: 119,700
Year
Topic
Type