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Keyword

thrombin generation

Description: Thrombin generation is the production of the blood-clotting enzyme thrombin during coagulation, studied in hemostasis and thrombosis.
OpenAlex ID: keywords/thrombin-generation
The Nature and Significance of Platelet Products in Human Plasma
1967 · Peter Wolf · British Journal of Haematology · 1,722
A Cell-based Model of Hemostasis
2001 · Dougald Monroe, Maureane Hoffman · Thrombosis and Haemostasis · 1,544
Calibrated Automated Thrombin Generation Measurement in Clotting Plasma
2003 · H. Coenraad Hemker, Peter Giesen, et al. · Pathophysiology of Haemostasis and Thrombosis · 1,431
Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes
2004 · Maud B. Gorbet, Michael V. Sefton · Biomaterials · 1,346
New Fundamentals in Hemostasis
2013 · Henri H. Versteeg, Johan W. M. Heemskerk, et al. · Physiological Reviews · 1,133
Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity
2015 · Deborah M. Siegal, John T. Curnutte, et al. · New England Journal of Medicine · 1,053
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Inflammation and coagulation
2010 · Marcel Levi, Tom van der Poll · Critical Care Medicine · 988
Efficacy and Safety of Tifacogin (Recombinant Tissue Factor Pathway Inhibitor) in Severe Sepsis
2003 · Edward Abraham, Konrad Reinhart, et al. · JAMA · 960
The Coagulopathy of Trauma: A Review of Mechanisms
2008 · John R. Hess, Karim Brohi, et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 943
Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4
2011 · Fabrizio Semeraro, Concetta T. Ammollo, et al. · Blood · 869
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Coagulation and sepsis
2016 · Marcel Levi, Tom van der Poll · Thrombosis Research · 853
Trauma-induced coagulopathy
2021 · Ernest E. Moore, Hunter B. Moore, et al. · Nature Reviews Disease Primers · 851
Fibrinolysis and the control of blood coagulation
2014 · John C. Chapin, Katherine A. Hajjar · Blood Reviews · 842
Preparation of Suspensions of Washed Platelets from Humans
1972 · J. F. Mustard, D. W. Perry, et al. · British Journal of Haematology · 832
Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties
2008 · Shin-Yeu Ong, Jian Wu, et al. · Biomaterials · 831
Chemokines in the Pathogenesis of Vascular Disease
2004 · Israel F. Charo, Mark B. Taubman · Circulation Research · 753
Thrombin generation and fibrin clot structure
2007 · Alisa S. Wolberg · Blood Reviews · 748
Acute Coagulopathy of Trauma: Hypoperfusion Induces Systemic Anticoagulation and Hyperfibrinolysis
2008 · Karim Brohi, Mitchell J. Cohen, et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 737
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The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor
1996 · David W. Banner, Allan D'Arcy, et al. · Nature · 731
High Levels of Coagulation Factor XI as a Risk Factor for Venous Thrombosis
2000 · Joost C.M. Meijers, Winnie L.H. Tekelenburg, et al. · New England Journal of Medicine · 701
Evidence of normal thrombin generation in cirrhosis despite abnormal conventional coagulation tests†‡
2005 · Armando Tripodi, Francesco Salerno, et al. · Hepatology · 696
Platelets and Thrombin Generation
2002 · Dougald M. Monroe, Maureane Hoffman, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 681
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The Calibrated Automated Thrombogram (CAT): a universal routine test for hyper- and hypocoagulability
2002 · H.C. Hemker, P. Giesen, et al. · Pathophysiology of Haemostasis and Thrombosis · 680
Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity.
1988 · P J Sims, E M Faioni, et al. · Journal of Biological Chemistry · 673
Endothelial and Antithrombotic Actions of HDL
2006 · Chieko Mineo, Hiroshi Deguchi, et al. · Circulation Research · 656
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Works count: 11,180
Citation count: 283,700
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