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Keyword

thyA

Description: thyA is a gene encoding thymidylate synthase, an enzyme involved in nucleotide synthesis and studied in microbial genetics and drug resistance.
OpenAlex ID: keywords/thya
An Alternative Flavin-Dependent Mechanism for Thymidylate Synthesis
2002 · Hannu Myllykallio, Gerard Lipowski, et al. · Science · 288
RECOMBINATION DEFICIENT MUTANTS OF ESCHERICHIA COLI K12 THAT MAP BETWEEN thyA AND argA
1968 · Peter T Emmerson · Genetics · 168
Genetic Analysis of Recombination-Deficient Mutants of Escherichia coli K-12 Carrying rec Mutations Cotransducible with thyA
1969 · Neil S. Willetts, David W. Mount · Journal of Bacteriology · 165
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Enhanced protein and biochemical production using CRISPRi-based growth switches
2016 · Songyuan Li, Christian Bille Jendresen, et al. · Metabolic Engineering · 95
Mycobacterium tuberculosis thymidylate synthase gene thyX is essential and potentially bifunctional, while thyA deletion confers resistance to p-aminosalicylic acid
2011 · Amanda S. Fivian-Hughes, Joanna Houghton, et al. · Microbiology · 93
Inactivation of thyA in Staphylococcus aureus Attenuates Virulence and Has a Strong Impact on Metabolism and Virulence Gene Expression
2014 · Andre Kriegeskorte, Desiree Block, et al. · mBio · 89
Regulation of diaminopimelate decarboxylase synthesis in Escherichia coli
1983 · Patrick Stragier, François Richaud, et al. · Journal of Molecular Biology · 89
Genetic control of DNA initiation in Escherichia coli
1973 · W.H. Schubach, J.D. Whetmer, et al. · Journal of Molecular Biology · 84
Synthesis and Evaluation of 5-Substituted 2′-deoxyuridine Monophosphate Analogues As Inhibitors of Flavin-Dependent Thymidylate Synthase inMycobacterium tuberculosis
2011 · Martin Kögler, Bart Vanderhoydonck, et al. · Journal of Medicinal Chemistry · 77
Isolation of peptide aptamers that inhibit intracellular processes
2000 · Jonathan H. Blum, Simon L. Dove, et al. · Proceedings of the National Academy of Sciences · 72
Isolation and characterization of a temperature-sensitive mutant of Salmonella typhimurium defective in prolipoprotein modification
1993 · K. Gan, S.D. Gupta, et al. · Journal of Biological Chemistry · 63
Cas9-assisted biological containment of a genetically engineered human commensal bacterium and genetic elements
2024 · Naoki Hayashi, Yong Lai, et al. · Nature Communications · 62
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Identification of Staphylococcus aureus Factors Required for Pathogenicity and Growth in Human Blood
2017 · John Connolly, Emma Boldock, et al. · Infection and Immunity · 62
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Tn10 insertional mutations of Bacillus subtilis that block the biosynthesis of bacilysin
2001 · Ayten Yazgan, Gülay Özcengiz, et al. · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 60
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity
1991 · L. Hsu, S. Jackowski, et al. · Journal of Biological Chemistry · 60
Genetic markers for Clostridium difficile lineages linked to hypervirulence
2011 · Cornelis W. Knetsch, Marjolein P. M. Hensgens, et al. · Microbiology · 54
Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 Å resolution
2002 · Peter Kuhn, Scott A. Lesley, et al. · Proteins Structure Function and Bioinformatics · 54
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Functional evidence for active site location of tetrameric thymidylate synthase X at the interphase of three monomers
2004 · Damien Leduc, Sébastien Graziani, et al. · Proceedings of the National Academy of Sciences · 53
Mutagenesis via IS transposition in Deinococcus radiodurans
2005 · Samuel Mennecier, Pascale Servant, et al. · Molecular Microbiology · 52
Related homing endonucleases I- Bmo I and I- Tev I use different strategies to cleave homologous recognition sites
2001 · David R. Edgell, David A. Shub · Proceedings of the National Academy of Sciences · 52
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Synthesis and Evaluation of 6‐Aza‐2′‐deoxyuridine Monophosphate Analogs as Inhibitors of Thymidylate Synthases, and as Substrates or Inhibitors of Thymidine Monophosphate Kinase in Mycobacterium tuberculosis
2012 · Martin Kögler, Roger Busson, et al. · Chemistry & Biodiversity · 48
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Mating and spermatophore morphology of water mites (Acari: Parasitengona)
1992 · HEATHER C. PROCTOR · Zoological Journal of the Linnean Society · 48
Genetics of Bacillus subtilis chemotaxis: isolation and mapping of mutations and cloning of chemotaxis genes
1983 · G W Ordal, D O Nettleton, et al. · Journal of Bacteriology · 48
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Increase in Furfural Tolerance in Ethanologenic Escherichia coli LY180 by Plasmid-Based Expression of thyA
2012 · Huabao Zheng, Xuan Wang, et al. · Applied and Environmental Microbiology · 43
Kinetics and Ligand-Binding Preferences of Mycobacterium tuberculosis Thymidylate Synthases, ThyA and ThyX
2008 · Joshua H. Hunter, Ramesh Gujjar, et al. · PLoS ONE · 42
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Works count: 1,233
Citation count: 3,073
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