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Keyword

thymic selection

Description: Thymic selection is the process by which developing T cells are selected in the thymus based on their ability to recognize self-MHC and avoid strong self-reactivity.
OpenAlex ID: keywords/thymocyte-selection
Regulatory T Cells and Immune Tolerance
2008 · Shimon Sakaguchi, Tomoyuki Yamaguchi, et al. · Cell · 5,335
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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
1991 · I. Nicoletti, G. Migliorati, et al. · Journal of Immunological Methods · 4,579
N aturally A rising CD4+R egulatory T C ells for I mmunologic S elf -T olerance and N egative C ontrol of I mmune R esponses
2003 · Shimon Sakaguchi · Annual Review of Immunology · 3,307
T-cell antigen receptor genes and T-cell recognition
1988 · Mark M. Davis, Pamela J. Bjorkman · Nature · 3,200
T cell tolerance by clonal elimination in the thymus
1987 · John W. Kappler, Neal Roehm, et al. · Cell · 2,213
The Biology of NKT Cells
2006 · Albert Bendelac, Paul B. Savage, et al. · Annual Review of Immunology · 2,164
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
1988 · Pawel Kisielow, Horst Blüthmann, et al. · Nature · 1,682
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
2001 · Martha S. Jordan, Alina Boesteanu, et al. · Nature Immunology · 1,662
Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
2001 · Shimon Sakaguchi, Noriko Sakaguchi, et al. · Immunological Reviews · 1,506
Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance
1999 · Misako Itoh, Takeshi Takahashi, et al. · The Journal of Immunology · 1,211
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Human autoimmune diseases: a comprehensive update
2015 · Lifeng Wang, Fu‐Sheng Wang, et al. · Journal of Internal Medicine · 1,173
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 · Ralph Marvin Steinman, Michel C. Nussenzweig · Proceedings of the National Academy of Sciences · 1,167
T-cell apoptosis detected in situ during positive and negative selection in the thymus
1994 · Charles D. Surh, Jonathan Sprent · Nature · 1,067
An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.
1994 · O Lantz, A Bendelac · The Journal of Experimental Medicine · 1,057
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Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?
2009 · Maria A. Curotto de Lafaille, Juan J. Lafaille · Immunity · 1,055
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bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
1991 · Andreas Strasser, Alan W. Harris, et al. · Cell · 1,054
TOWARD AN UNDERSTANDING OF NKT CELL BIOLOGY: Progress and Paradoxes
2005 · Mitchell Kronenberg · Annual Review of Immunology · 1,029
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
1989 · Hanspeter Pircher, Kurt Bürki, et al. · Nature · 1,019
FOXP3: Of Mice and Men
2005 · Steven F. Ziegler · Annual Review of Immunology · 922
T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens
1988 · H. Robson MacDonald, Reto Schneider, et al. · Nature · 888
Mice lacking MHC class II molecules
1991 · Dominic Cosgrove, David Gray, et al. · Cell · 852
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Gamma/Delta Cells
1993 · W Haas, P Pereira, et al. · Annual Review of Immunology · 808
Glucocorticoids in T Cell Development and Function
2000 · Jonathan D. Ashwell, Frank W. M. Lu, et al. · Annual Review of Immunology · 783
Selecting and maintaining a diverse T-cell repertoire
1999 · Ananda W. Goldrath, Michael J. Bevan · Nature · 777
Journey through the thymus: stromal guides for T-cell development and selection
2006 · Yousuke Takahama · Nature reviews. Immunology · 728
Works count: 4,505
Citation count: 176,100
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