Keyword

tight junctions

Description: Cellular junctions that seal neighboring cells and regulate the passage of substances between them, especially in epithelial tissues.

Primary topic: Barrier Structure and Function Studies (25%)

Wikidata ID: wiki/Q1053832

OpenAlex ID: keywords/tight-junctions

Structure and function of the blood–brain barrier

2009 · N. Joan Abbott, Adjanie A.K. Patabendige, et al. · Neurobiology of Disease · 5,167

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice

2008 · Patrice D. Cani, Rodrigo Bibiloni, et al. · Diabetes · 4,811

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High-yield Preparation of Isolated Rat Liver Parenchymal Cells

1969 · M. N. Berry, D. S. Friend · The Journal of Cell Biology · 4,425

Junctional Complexes in Various Epithelia

1963 · Marilyn G. Farquhar, George E. Palade · The Journal of Cell Biology · 3,636

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The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

2008 · Berislav V. Zlokovic · Neuron · 3,274

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Pericytes regulate the blood–brain barrier

2010 · Annika Armulik, Guillem Genové, et al. · Nature · 2,843

The Blood-Brain Barrier/Neurovascular Unit in Health and Disease

2005 · Brian T. Hawkins, Thomas P. Davis · Pharmacological Reviews · 2,662

Fine Structural Localization of a Blood-brain Barrier to Exogenous Peroxidase

1967 · T. S. Reese, Morris J. Karnovsky · The Journal of Cell Biology · 2,629

Occludin: a novel integral membrane protein localizing at tight junctions.

1993 · M Furuse, T Hirase, et al. · The Journal of Cell Biology · 2,580

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

2001 · Maria Rescigno, Matteo Urbano, et al. · Nature Immunology · 2,556

Multifunctional strands in tight junctions

2001 · Shoichiro Tsukita, Mikio Furuse, et al. · Nature Reviews Molecular Cell Biology · 2,512

Junctions Between Intimately Apposed Cell Membranes in the Vertebrate Brain

1969 · M. W. Brightman, T. S. Reese · The Journal of Cell Biology · 2,471

The blood–brain barrier: an overview

2004 · Praveen Ballabh, Alex Braun, et al. · Neurobiology of Disease · 2,265

Pericytes are required for blood–brain barrier integrity during embryogenesis

2010 · Richard Daneman, Lu Zhou, et al. · Nature · 2,129

Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

1998 · Mikio Furuse, Kohji Fujita, et al. · The Journal of Cell Biology · 2,095

The skin: an indispensable barrier

2008 · Ehrhardt Proksch, Johanna M. Brandner, et al. · Experimental Dermatology · 2,047

Drug Transport across the Blood–Brain Barrier

2012 · William M Pardridge · Journal of Cerebral Blood Flow & Metabolism · 1,987

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Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice

2003 · Takehiro Nitta, Masaki Hata, et al. · The Journal of Cell Biology · 1,913

Intestinal barrier function: Molecular regulation and disease pathogenesis

2009 · Katherine R. Groschwitz, Simon P. Hogan · Journal of Allergy and Clinical Immunology · 1,772

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

2007 · Hania Kebir, Katharina Kreymborg, et al. · Nature Medicine · 1,757

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

1986 · B R Stevenson, J D Siliciano, et al. · The Journal of Cell Biology · 1,638

Astrocytes induce blood–brain barrier properties in endothelial cells

1987 · Robert C. Janzer, Martin C. Raff · Nature · 1,626

Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton

2007 · Andrea Hartsock, W. James Nelson · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1,558

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Claudin-based tight junctions are crucial for the mammalian epidermal barrier

2002 · Mikio Furuse, Masaki Hata, et al. · The Journal of Cell Biology · 1,513

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Tight junctions: from simple barriers to multifunctional molecular gates

2016 · Ceniz Zihni, Clare Mills, et al. · Nature Reviews Molecular Cell Biology · 1,501

Works count: 29,260

Citation count: 1,119,000