Keyword

tissue factor

Description: A cell-surface protein that initiates the blood coagulation cascade and links inflammatory processes with thrombosis.

Primary topic: Blood Coagulation and Thrombosis Mechanisms (41%)

Wikidata ID: wiki/Q412841

OpenAlex ID: keywords/tissue-factor

Structural design and molecular evolution of a cytokine receptor superfamily.

1990 · J F Bazan · Proceedings of the National Academy of Sciences · 2,071

Mechanisms of Thrombus Formation

2008 · Bruce Furie, Barbara C. Furie · New England Journal of Medicine · 1,928

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

2012 · Marie-Luise von Brühl, Konstantin Stark, et al. · The Journal of Experimental Medicine · 1,830

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Atherosclerosis: Basic Mechanisms

1995 · Judith A. Berliner, Mohamad Navab, et al. · Circulation · 1,724

Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection

2008 · Lewis H Kuller, Russell Tracy, et al. · PLoS Medicine · 1,618

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A Cell-based Model of Hemostasis

2001 · Dougald Monroe, Maureane Hoffman · Thrombosis and Haemostasis · 1,544

Dendritic-cell control of pathogen-driven T-cell polarization

2003 · Martien L. Kapsenberg · Nature reviews. Immunology · 1,438

Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes

2004 · Maud B. Gorbet, Michael V. Sefton · Biomaterials · 1,346

Modulation of endothelial cell hemostatic properties by tumor necrosis factor.

1986 · P P Nawroth, D M Stern · The Journal of Experimental Medicine · 1,311

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Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque.

1989 · J N Wilcox, K M Smith, et al. · Proceedings of the National Academy of Sciences · 1,214

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

2010 · Steffen Massberg, Lenka Grahl, et al. · Nature Medicine · 1,207

Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis.

1989 · T A Drake, J H Morrissey, et al. · PubMed · 1,192

Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE

2001 · Marie-Paule Wautier, Olivier Chappey, et al. · American Journal of Physiology-Endocrinology and Metabolism · 1,075

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.

1986 · M P Bevilacqua, J S Pober, et al. · Proceedings of the National Academy of Sciences · 1,067

Tissue-factor–bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation

2005 · Ian del Conde, Corie N. Shrimpton, et al. · Blood · 1,029

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Blood-borne tissue factor: Another view of thrombosis

1999 · Peter L. A. Giesen, Ursula Rauch, et al. · Proceedings of the National Academy of Sciences · 991

Inflammation and coagulation

2010 · Marcel Levi, Tom van der Poll · Critical Care Medicine · 988

Efficacy and Safety of Tifacogin (Recombinant Tissue Factor Pathway Inhibitor) in Severe Sepsis

2003 · Edward Abraham, Konrad Reinhart, et al. · JAMA · 960

Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells.

1984 · M P Bevilacqua, J S Pober, et al. · The Journal of Experimental Medicine · 935

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Fibrinogen as a key regulator of inflammation in disease

2011 · Dimitrios Davalos, Katerina Akassoglou · Seminars in Immunopathology · 925

Tissue factor and hemostasis [published erratum appears in Blood 1988 Apr;71(4):1178]

1988 · Y Nemerson · Blood · 920

Drug-Eluting Stent and Coronary Thrombosis

2007 · Thomas F. Lüscher, Jan Steffel, et al. · Circulation · 906

Elevated Levels of Shed Membrane Microparticles With Procoagulant Potential in the Peripheral Circulating Blood of Patients With Acute Coronary Syndromes

2000 · Ziad Mallat, Hakim Benamer, et al. · Circulation · 883

Surface-dependent reactions of the vitamin K-dependent enzyme complexes

1990 · KG Mann, ME Nesheim, et al. · Blood · 879

Angiotensin II Type 1–Receptor Activating Antibodies in Renal-Allograft Rejection

2005 · Duska Dragun, Dominik N. Müller, et al. · New England Journal of Medicine · 869

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Works count: 18,570

Citation count: 541,100