Keyword

TLR2

Description: Toll-like receptor 2, an innate immune system protein that recognizes microbial components and helps initiate inflammatory responses.

Primary topic: Immune Response and Inflammation (27%)

OpenAlex ID: keywords/tlr2

Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components

1999 · Osamu Takeuchi, Katsuaki Hoshino, et al. · Immunity · 3,362

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

2007 · Luke A. J. O'Neill, Andrew G. Bowie · Nature reviews. Immunology · 2,675

TLR signaling pathways

2004 · Kiyoshi Takeda, Shizuo Akira · Seminars in Immunology · 2,467

Inducible Foxp3 + regulatory T-cell development by a commensal bacterium of the intestinal microbiota

2010 · June L. Round, Sarkis K. Mazmanian · Proceedings of the National Academy of Sciences · 2,234

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

2016 · Hubert Plovier, Amandine Everard, et al. · Nature Medicine · 2,201

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors

2000 · Adrian Ozinsky, David M. Underhill, et al. · Proceedings of the National Academy of Sciences · 2,085

Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens

2001 · Norimitsu Kadowaki, Stephen Ho, et al. · The Journal of Experimental Medicine · 1,966

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TLR4 enhances TGF-β signaling and hepatic fibrosis

2007 · Ekihiro Seki, Samuele De Minicis, et al. · Nature Medicine · 1,943

Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides

2002 · Veit Hornung, Simon Rothenfusser, et al. · The Journal of Immunology · 1,936

A family of human receptors structurally related to Drosophila Toll

1998 · Fernando L. Rock, Gary Hardiman, et al. · Proceedings of the National Academy of Sciences · 1,728

Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

1999 · Ralf Schwandner, Roman Dziarski, et al. · Journal of Biological Chemistry · 1,703

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Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2

2003 · Naohiro Inohara, Yasunori Ogura, et al. · Journal of Biological Chemistry · 1,696

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TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

2011 · A. Phillip West, Igor E. Brodsky, et al. · Nature · 1,652

Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2

2003 · Benjamin N. Gantner, Randi M. Simmons, et al. · The Journal of Experimental Medicine · 1,645

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

2011 · June L. Round, S. Melanie Lee, et al. · Science · 1,605

Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein

2004 · Jong Sung Park, Daiva Svetkauskaite, et al. · Journal of Biological Chemistry · 1,562

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Novel Signal Transduction Pathway Utilized by Extracellular HSP70

2002 · Alexzander Asea, Michael Rehli, et al. · Journal of Biological Chemistry · 1,509

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Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2

1999 · Antonios O. Aliprantis, Ruey-Bing Yang, et al. · Science · 1,474

HMGB1 and RAGE in Inflammation and Cancer

2010 · Gary P. Sims, Daniel C. Rowe, et al. · Annual Review of Immunology · 1,435

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

2005 · Dianhua Jiang, Jiurong Liang, et al. · Nature Medicine · 1,400

Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

2002 · Christian Termeer, Frauke Benedix, et al. · The Journal of Experimental Medicine · 1,377

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

1999 · David M. Underhill, Adrian Ozinsky, et al. · Nature · 1,368

Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide

2007 · Mi Sun Jin, Sung Eun Kim, et al. · Cell · 1,345

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The immune response to Prevotella bacteria in chronic inflammatory disease

2017 · Jeppe Madura Larsen · Immunology · 1,339

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Cutting Edge: Role of Toll-Like Receptor 1 in Mediating Immune Response to Microbial Lipoproteins

2002 · Osamu Takeuchi, Shintaro Sato, et al. · The Journal of Immunology · 1,329

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Works count: 22,750

Citation count: 769,900