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TLR7
Description:
Toll-like receptor 7, an innate immune system receptor that recognizes certain molecular patterns and helps trigger immune responses.
Primary topic:
Immune Response and Inflammation (28%)
Related topics:
Immune Response and Inflammation (28%),
Systemic Lupus Erythematosus Research (11%)
OpenAlex ID:
keywords/tlr7
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004
·
Florian Heil
, Hiroaki Hemmi
, et al.
·
Science
·
3,944
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
2004
·
Sandra S. Diebold
, Tsuneyasu Kaisho
, et al.
·
Science
·
3,444
Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA
2005
·
Katalin Karikó
, Michael Buckstein
, et al.
·
Immunity
·
2,717
PDF
Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway
2002
·
Hiroaki Hemmi
, Tsuneyasu Kaisho
, et al.
·
Nature Immunology
·
2,523
Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens
2001
·
Norimitsu Kadowaki
, Stephen Ho
, et al.
·
The Journal of Experimental Medicine
·
1,967
PDF
Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides
2002
·
Veit Hornung
, Simon Rothenfusser
, et al.
·
The Journal of Immunology
·
1,937
Recognition of single-stranded RNA viruses by Toll-like receptor 7
2004
·
Jennifer M. Lund
, Lena Alexopoulou
, et al.
·
Proceedings of the National Academy of Sciences
·
1,862
IPC: Professional Type 1 Interferon-Producing Cells and Plasmacytoid Dendritic Cell Precursors
2004
·
Yong-Jun Liu
·
Annual Review of Immunology
·
1,626
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
2012
·
Muller Fabbri
, Alessio Paone
, et al.
·
Proceedings of the National Academy of Sciences
·
1,554
Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors
2010
·
Jérôme Cros
, Nicolas Cagnard
, et al.
·
Immunity
·
1,251
PDF
Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
2005
·
Veit Hornung
, Margit Guenthner-Biller
, et al.
·
Nature Medicine
·
1,232
Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling
2002
·
Masahiro Yamamoto
, Shintaro Sato
, et al.
·
The Journal of Immunology
·
1,227
PDF
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases
2008
·
Michel Gilliet
, Wei Cao
, et al.
·
Nature reviews. Immunology
·
1,187
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells
2005
·
Giorgio Napolitani
, Andrea Rinaldi
, et al.
·
Nature Immunology
·
1,157
Recognition of pathogen-associated molecular patterns by TLR family
2003
·
Shizuo Akira
, Hiroaki Hemmi
·
Immunology Letters
·
1,150
Toll-like Receptor 7 and TLR9 Dictate Autoantibody Specificity and Have Opposing Inflammatory and Regulatory Roles in a Murine Model of Lupus
2006
·
Sean R. Christensen
, Jonathan Shupe
, et al.
·
Immunity
·
1,089
PDF
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
2018
·
Scott A. Jenks
, Kevin S. Cashman
, et al.
·
Immunity
·
1,074
PDF
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
2004
·
Taro Kawai
, Shintaro Sato
, et al.
·
Nature Immunology
·
1,035
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
2002
·
Marion Jurk
, Florian Heil
, et al.
·
Nature Immunology
·
1,013
Toll‐like Receptor and RIG‐1‐like Receptor Signaling
2008
·
Taro Kawai
, Shizuo Akira
·
Annals of the New York Academy of Sciences
·
987
Programming the magnitude and persistence of antibody responses with innate immunity
2011
·
Sudhir Pai Kasturi
, Ioanna Skountzou
, et al.
·
Nature
·
975
Regulatory T Cells Selectively Express Toll-like Receptors and Are Activated by Lipopolysaccharide
2003
·
Iris Caramalho
, Thiago Lopes-Carvalho
, et al.
·
The Journal of Experimental Medicine
·
970
PDF
Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
2005
·
Franck J. Barrat
, Thea Meeker
, et al.
·
The Journal of Experimental Medicine
·
928
Autoreactive B Cell Responses to RNA-Related Antigens Due to TLR7 Gene Duplication
2006
·
Prapaporn Pisitkun
, Jonathan A. Deane
, et al.
·
Science
·
895
Autophagy-Dependent Viral Recognition by Plasmacytoid Dendritic Cells
2007
·
Heung Kyu Lee
, Jennifer M. Lund
, et al.
·
Science
·
864
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Works count:
6,417
Citation count:
219,100
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