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Keyword

TLR8

Description: A toll-like receptor protein encoded by the TLR8 gene that senses nucleic acids and contributes to innate immune responses.
Wikidata ID: wiki/Q15332524
OpenAlex ID: keywords/tlr8
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 · Florian Heil, Hiroaki Hemmi, et al. · Science · 3,942
Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA
2005 · Katalin Karikó, Michael Buckstein, et al. · Immunity · 2,716
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MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
2012 · Muller Fabbri, Alessio Paone, et al. · Proceedings of the National Academy of Sciences · 1,554
Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors
2010 · Jérôme Cros, Nicolas Cagnard, et al. · Immunity · 1,251
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Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells
2005 · Giorgio Napolitani, Andrea Rinaldi, et al. · Nature Immunology · 1,157
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
2004 · Taro Kawai, Shintaro Sato, et al. · Nature Immunology · 1,034
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
2002 · Marion Jurk, Florian Heil, et al. · Nature Immunology · 1,012
Emerging Role of Endosomal Toll-Like Receptors in Rheumatoid Arthritis
2014 · Ryan Thwaites, Giselle Chamberlain, et al. · Frontiers in Immunology · 748
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Toll-Like Receptor 8-Mediated Reversal of CD4 + Regulatory T Cell Function
2005 · Guangyong Peng, Zhong Guo, et al. · Science · 747
Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
2009 · Dipyaman Ganguly, Georgios Chamilos, et al. · The Journal of Experimental Medicine · 740
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Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1
2012 · Tatsuya Saitoh, Jun Komano, et al. · Cell Host & Microbe · 729
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Synthetic TLR Agonists Reveal Functional Differences between Human TLR7 and TLR8
2005 · Keith B Gorden, Kevin S Gorski, et al. · The Journal of Immunology · 683
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8α+ dendritic cells
2010 · Lionel Franz Poulin, Mariolina Salio, et al. · The Journal of Experimental Medicine · 671
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Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren’s syndrome
2006 · Jacques-Eric Gottenberg, Nicolas Cagnard, et al. · Proceedings of the National Academy of Sciences · 611
Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines
2011 · Alenka Kužnik, Mojca Benčina, et al. · The Journal of Immunology · 607
Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7
2003 · Jongdae Lee, Tsung-Hsien Chuang, et al. · Proceedings of the National Academy of Sciences · 593
Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity
2006 · Troy Querec, Soumaya Bennouna, et al. · The Journal of Experimental Medicine · 552
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Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response
2010 · Alexander Panda, Feng Qian, et al. · The Journal of Immunology · 547
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Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
2007 · Kensuke Miyake · Seminars in Immunology · 523
The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
2003 · Florian Heil, Parviz Ahmad‐Nejad, et al. · European Journal of Immunology · 518
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Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
2005 · Jörg Vollmer, Sibylle Tluk, et al. · The Journal of Experimental Medicine · 513
Toll-like Receptors and Type I Interferons
2007 · Satoshi Uematsu, Shizuo Akira · Journal of Biological Chemistry · 500
Three novel mammalian toll-like receptors: gene structure, expression, and evolution.
2000 · X Du, A Poltorak, et al. · PubMed · 460
Antiviral Signaling Through Pattern Recognition Receptors
2006 · T. Kawai, S. Akira · The Journal of Biochemistry · 451
Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA
2016 · Zhikuan Zhang, Umeharu Ohto, et al. · Immunity · 450
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Works count: 2,342
Citation count: 81,000
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