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Keyword

toxin A

Description: Toxin A is a cytotoxic protein produced by Clostridioides difficile that damages intestinal cells and contributes to disease.
OpenAlex ID: keywords/toxin-a
Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
2005 · Michel Warny, Jacques Pepin, et al. · The Lancet · 1,430
Glucosylation of Rho proteins by Clostridium difficile toxin B
1995 · I. Just, J. Selzer, et al. · Nature · 1,032
Asymptomatic Carriage ofClostridium difficileand Serum Levels of IgG Antibody against Toxin A
2000 · Lorraine Kyne, Michel Warny, et al. · New England Journal of Medicine · 935
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Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection
2017 · Mark H. Wilcox, Dale N. Gerding, et al. · New England Journal of Medicine · 858
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The role of toxin A and toxin B in Clostridium difficile infection
2010 · Sarah A. Kuehne, Stephen T. Cartman, et al. · Nature · 855
Clostridium difficile infection
2016 · Wiep Klaas Smits, Dena Lyras, et al. · Nature Reviews Disease Primers · 854
Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea
2001 · Lorraine Kyne, Michel Warny, et al. · The Lancet · 804
Treatment with Monoclonal Antibodies against Clostridium difficile Toxins
2010 · Israel Lowy, Deborah C. Molrine, et al. · New England Journal of Medicine · 746
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Toxin B is essential for virulence of Clostridium difficile
2009 · Dena Lyras, Jennifer R. O’Connor, et al. · Nature · 745
Emergence ofClostridium difficileInfection Due to a New Hypervirulent Strain, Polymerase Chain Reaction Ribotype 078
2008 · Abraham Goorhuis, Dennis Bakker, et al. · Clinical Infectious Diseases · 637
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Clostridium difficile: its disease and toxins
1988 · D M Lyerly, H C Krivan, et al. · Clinical Microbiology Reviews · 576
Clostridium difficile colitis: pathogenesis and host defence
2016 · Michael C. Abt, Peter T. McKenney, et al. · Nature Reviews Microbiology · 551
Clostridium difficile Infection
1998 · Ciarán P. Kelly, J. Thomas LaMont · Annual Review of Medicine · 420
European Society of Clinical Microbiology and Infectious Diseases (ESCMID): Data review and recommendations for diagnosing Clostridium difficile-infection (CDI)
2009 · M.J.T. Crobach, O.M. Dekkers, et al. · Clinical Microbiology and Infection · 413
Saccharomyces boulardii Protease Inhibits the Effects of Clostridium difficile Toxins A and B in Human Colonic Mucosa
1999 · Ignazio Castagliuolo, Martin F. Riegler, et al. · Infection and Immunity · 408
Effects of Clostridium difficile toxins given intragastrically to animals
1985 · D M Lyerly, K E Saum, et al. · Infection and Immunity · 400
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Purification and characterization of toxins A and B of Clostridium difficile
1982 · N M Sullivan, S Pellett, et al. · Infection and Immunity · 368
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Identification of Toxin A-Negative, Toxin B-Positive Clostridium difficile by PCR
1998 · Haru Kato, Naoki Kato, et al. · Journal of Clinical Microbiology · 357
The role of toxins in Clostridium difficile infection
2017 · Ramyavardhanee Chandrasekaran, D. Borden Lacy · FEMS Microbiology Reviews · 353
Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro.
1995 · M Riegler, R Sedivy, et al. · Journal of Clinical Investigation · 340
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Clostridium difficile--Associated diarrhea: A review.
2001 · E Mylonakis, E T Ryan, et al. · PubMed · 339
Multiplex PCR Targetingtpi(Triose Phosphate Isomerase),tcdA(Toxin A), andtcdB(Toxin B) Genes for Toxigenic Culture ofClostridium difficile
2004 · Ludovic Lemee, Anne Dhalluin, et al. · Journal of Clinical Microbiology · 337
Persistence and Toxin Production by Clostridium difficile within Human Intestinal Organoids Result in Disruption of Epithelial Paracellular Barrier Function
2014 · Jhansi L. Leslie, Sha Huang, et al. · Infection and Immunity · 330
Definition of the single integration site of the pathogenicity locus in Clostridium difficile
1996 · Veit Braun, Thomas Hundsberger, et al. · Gene · 330
Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections
2015 · Glen P. Carter, Anjana Chakravorty, et al. · mBio · 324
Works count: 1,935
Citation count: 57,480
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