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toxin internalization
Description:
The cellular uptake of toxins, a process studied in toxicology and cell biology for its role in toxin action.
Primary topic:
Toxin Mechanisms and Immunotoxins (28%)
Related topics:
Toxin Mechanisms and Immunotoxins (28%),
Botulinum Toxin and Related Neurological Disorders (14%),
Cellular transport and secretion (11%),
Clostridium difficile and Clostridium perfringens research (8%),
Escherichia coli research studies (8%)
OpenAlex ID:
keywords/toxin-internalization
Infection by verocytotoxin-producing Escherichia coli
1989
·
M A Karmali
·
Clinical Microbiology Reviews
·
1,322
Endocytosis
1997
·
S. Mukherjee
, R. N. Ghosh
, et al.
·
Physiological Reviews
·
1,319
SV2 Is the Protein Receptor for Botulinum Neurotoxin A
2006
·
Min Dong
, Felix Yeh
, et al.
·
Science
·
772
Shiga and Shiga-like toxins
1987
·
A D O'Brien
, R K Holmes
·
Microbiological Reviews
·
727
Filipin-dependent Inhibition of Cholera Toxin: Evidence for Toxin Internalization and Activation through Caveolae-like Domains
1998
·
Palmer A. Orlandi
, Peter H. Fishman
·
The Journal of Cell Biology
·
722
Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor
2003
·
Heather M. Scobie
, G. Jonah A. Rainey
, et al.
·
Proceedings of the National Academy of Sciences
·
612
Crystal structure of cholera toxin B‐pentamer bound to receptor G M1 pentasaccharide
1994
·
Ethan A. Merritt
, Steve Sarfaty
, et al.
·
Protein Science
·
572
PDF
Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins
1982
·
R. Montesano
, J. Roth
, et al.
·
Nature
·
426
Direct Pathway from Early/Recycling Endosomes to the Golgi Apparatus Revealed through the Study of Shiga Toxin B-fragment Transport
1998
·
Frédéric Mallard
, Claude Antony
, et al.
·
The Journal of Cell Biology
·
425
Internalization of cholera toxin by different endocytic mechanisms
2001
·
Maria L. Torgersen
, Grethe Skretting
, et al.
·
Journal of Cell Science
·
377
The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.
1980
·
R K Draper
, M I Simon
·
The Journal of Cell Biology
·
370
Accumulating Evidence Suggests That Several AB-Toxins Subvert the Endoplasmic Reticulum-Associated Protein Degradation Pathway To Enter Target Cells
1997
·
Bart Hazes
, Randy J. Read
·
Biochemistry
·
317
Immunotoxins for targeted cancer therapy
2006
·
Robert J. Kreitman
·
The AAPS Journal
·
308
PDF
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.
1981
·
K Sandvig
, S Olsnes
·
Journal of Biological Chemistry
·
290
Diphtheria toxin forms transmembrane channels in planar lipid bilayers.
1981
·
J J Donovan
, M I Simon
, et al.
·
Proceedings of the National Academy of Sciences
·
278
Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin
2002
·
Kirsten Sandvig
, Bo van Deurs
·
FEBS Letters
·
276
PDF
Release ofHelicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium
1999
·
Roberto Fiocca
, Vittorio Necchi
, et al.
·
The Journal of Pathology
·
274
Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
2000
·
K. Sandvig
, B. van Deurs
·
The EMBO Journal
·
256
PDF
Rafting with cholera toxin: endocytosis and trafficking from plasma membrane to ER
2006
·
Daniel J.-F. Chinnapen
, Himani Chinnapen
, et al.
·
FEMS Microbiology Letters
·
243
Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. I. Ultrastructural autoradiographic localization and quantitation of distinct membrane acceptors for types A and B on motor nerves.
1986
·
J D Black
, J O Dolly
·
The Journal of Cell Biology
·
235
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles.
1982
·
K Sandvig
, S Olsnes
·
Journal of Biological Chemistry
·
232
Gangliosides That Associate with Lipid Rafts Mediate Transport of Cholera and Related Toxins from the Plasma Membrane to Endoplasmic Reticulm
2003
·
Yukako Fujinaga
, Anne A. Wolf
, et al.
·
Molecular Biology of the Cell
·
231
Membrane Traffic Exploited by Protein Toxins
2002
·
Kirsten Sandvig
, Bo van Deurs
·
Annual Review of Cell and Developmental Biology
·
218
Association of diphtheria toxin with Vero cells. Demonstration of a receptor.
1978
·
J.L. Middlebrook
, R.B. Dorland
, et al.
·
Journal of Biological Chemistry
·
194
PDF
Domain Organization in Clostridium botulinum Neurotoxin Type E Is Unique: Its Implication in Faster Translocation
2008
·
Desigan Kumaran
, Subramaniam Eswaramoorthy
, et al.
·
Journal of Molecular Biology
·
189
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Works count:
856
Citation count:
33,880
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