Keyword

TPC1

Description: TPC1 is a two-pore ion channel protein involved in calcium signaling and intracellular membrane function, studied in plants and animals.

Primary topic: Calcium signaling and nucleotide metabolism (55%)

Wikidata ID: wiki/Q18040620

OpenAlex ID: keywords/tpc1

Salt stress-induced Ca 2+ waves are associated with rapid, long-distance root-to-shoot signaling in plants

2014 · Won-Gyu Choi, Masatsugu Toyota, et al. · Proceedings of the National Academy of Sciences · 662

The vacuolar Ca2+-activated channel TPC1 regulates germination and stomatal movement

2005 · Edgar Peiter, Frans J. M. Maathuis, et al. · Nature · 538

TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes

2012 · Xiang Wang, Xiaoli Zhang, et al. · Cell · 530

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

2009 · Eugen Brailoiu, Dev Churamani, et al. · The Journal of Cell Biology · 401

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mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State

2013 · Chunlei Cang, Yandong Zhou, et al. · Cell · 363

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Orchestrating rapid long‐distance signaling in plants with Ca2+, ROS and electrical signals

2017 · Won‐Gyu Choi, Gad Miller, et al. · The Plant Journal · 314

A ROS-Assisted Calcium Wave Dependent on the AtRBOHD NADPH Oxidase and TPC1 Cation Channel Propagates the Systemic Response to Salt Stress

2016 · Matthew J. Evans, Won-Gyu Choi, et al. · PLANT PHYSIOLOGY · 314

Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking

2010 · Margarida Ruas, Katja Rietdorf, et al. · Current Biology · 249

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Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana

2015 · Jiangtao Guo, Weizhong Zeng, et al. · Nature · 233

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Interplay of Plasma Membrane and Vacuolar Ion Channels, Together with BAK1, Elicits Rapid Cytosolic Calcium Elevations in Arabidopsis during Aphid Feeding

2017 · Thomas R. Vincent, Marieta Avramova, et al. · The Plant Cell · 200

Cation channels in the Arabidopsis plasma membrane

2002 · Anne-Aliénor Véry, Hervé Sentenac · Trends in Plant Science · 188

Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel

2018 · Ji She, Jiangtao Guo, et al. · Nature · 178

Molecular Cloning of a Novel Form (Two-Repeat) Protein Related to Voltage-Gated Sodium and Calcium Channels

2000 · Kenichi Ishibashi, Makoto Suzuki, et al. · Biochemical and Biophysical Research Communications · 172

Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana

2016 · Alexander F. Kintzer, Robert M. Stroud · Nature · 169

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Function and dysfunction of two-pore channels

2015 · Sandip Patel · Science Signaling · 164

The voltage-gated sodium channel TPC1 confers endolysosomal excitability

2014 · Chunlei Cang, Biruk Bekele, et al. · Nature Chemical Biology · 164

Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells*

2011 · Yaping Lin-Moshier, Timothy F. Walseth, et al. · Journal of Biological Chemistry · 161

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Expression of Ca2+‐permeable two‐pore channels rescues NAADP signalling in TPC‐deficient cells

2015 · Margarida Ruas, Lianne C Davis, et al. · The EMBO Journal · 157

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Thyroid cancer cell lines: an overview

2012 · Manuel Saiselet, Sébastien Floor, et al. · Frontiers in Endocrinology · 156

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A gain‐of‐function allele of TPC1 activates oxylipin biogenesis after leaf wounding in Arabidopsis

2007 · Gustavo Bonaventure, Aurélie Gfeller, et al. · The Plant Journal · 154

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TPC1 – SV Channels Gain Shape

2011 · Rainer Hedrich, Irene Marten · Molecular Plant · 153

The plant vacuole: Emitter and receiver of calcium signals

2011 · Edgar Peiter · Cell Calcium · 147

Vacuolar calcium channels

2007 · I. I. Pottosin, G. Schonknecht · Journal of Experimental Botany · 145

Intracellular sphingosine releases calcium from lysosomes

2015 · Doris Höglinger, Per Haberkant, et al. · eLife · 143

Calcium signaling via two-pore channels: local or global, that is the question

2009 · Michael X. Zhu, Jianjie Ma, et al. · American Journal of Physiology-Cell Physiology · 132

Works count: 286

Citation count: 11,250