Keyword

TRAF3

Description: TRAF3 is a protein-coding human gene that produces a signaling protein involved in immune regulation and tumor necrosis factor receptor pathways.

Primary topic: NF-κB Signaling Pathways (22%)

Wikidata ID: wiki/Q18032095

OpenAlex ID: keywords/traf3

TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40

1995 · Mike Rothe, Vidya Sarma, et al. · Science · 1,051

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

2005 · Hans Häcker, Vanessa Redecke, et al. · Nature · 968

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Frequent Engagement of the Classical and Alternative NF-κB Pathways by Diverse Genetic Abnormalities in Multiple Myeloma

2007 · Christina M. Annunziata, R. Eric Davis, et al. · Cancer Cell · 950

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Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

2005 · Gagik Oganesyan, Supriya K. Saha, et al. · Nature · 881

The noncanonical NF‐κB pathway

2012 · Shao‐Cong Sun · Immunological Reviews · 722

Resistin Promotes Endothelial Cell Activation

2003 · Subodh Verma, Shu-Hong Li, et al. · Circulation · 670

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

2008 · Sivakumar Vallabhapurapu, Atsushi Matsuzawa, et al. · Nature Immunology · 608

Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK

2008 · Brian J Zarnegar, Yaya Wang, et al. · Nature Immunology · 604

NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling

2012 · Irving C. Allen, Justin E. Wilson, et al. · Immunity · 534

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Severe acute respiratory syndrome Coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3‐dependent ubiquitination of ASC

2019 · Kam‐Leung Siu, Kit‐San Yuen, et al. · The FASEB Journal · 502

Death receptor signaling

2005 · Inna Lavrik, Alexander Golks, et al. · Journal of Cell Science · 494

Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr Virus LMP1 Domain Important for B-Lymphocyte Transformation: Role in NF-κB Activation

1996 · Odile Devergne, Eudoxia Hatzivassiliou, et al. · Molecular and Cellular Biology · 491

SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome

2014 · Chong-Shan Shi, Hai-Yan Qi, et al. · The Journal of Immunology · 473

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Expanding TRAF function: TRAF3 as a tri-faced immune regulator

2011 · Hans Häcker, Ping-Hui Tseng, et al. · Nature reviews. Immunology · 471

Regulation of the NF-κB-inducing Kinase by Tumor Necrosis Factor Receptor-associated Factor 3-induced Degradation

2004 · Gongxian Liao, Minying Zhang, et al. · Journal of Biological Chemistry · 465

The TRAF Family of Signal Transducers Mediates NF-κB Activation by the TRANCE Receptor

1998 · Brian R. Wong, Régis Josien, et al. · Journal of Biological Chemistry · 458

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A Deubiquitinase That Regulates Type I Interferon Production

2007 · Nobuhiko Kayagaki, Qui Phung, et al. · Science · 452

Tumor Necrosis Factor Receptor-Associated Factor (TRAF) Family: Adapter Proteins That Mediate Cytokine Signaling

2000 · Jun-ichiro Inoue, Takaomi Ishida, et al. · Experimental Cell Research · 447

Toll-like receptors: Significance, ligands, signaling pathways, and functions in mammals

2017 · Mallenahally Kusha Vidya, V. Girish Kumar, et al. · International Reviews of Immunology · 442

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

2006 · Supriya K Saha, Eric M Pietras, et al. · The EMBO Journal · 423

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Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions

2021 · Daniel F. Levey, Murray B. Stein, et al. · Nature Neuroscience · 422

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Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

2009 · Ping-Hui Tseng, Atsushi Matsuzawa, et al. · Nature Immunology · 387

A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in Angiogenesis

2001 · Steven R Wiley, Linda Cassiano, et al. · Immunity · 377

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The RNA helicase DDX46 inhibits innate immunity by entrapping m6A-demethylated antiviral transcripts in the nucleus

2017 · Qingliang Zheng, Jin Hou, et al. · Nature Immunology · 368

4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB

1998 · Robert H. Arch, Craig B. Thompson · Molecular and Cellular Biology · 356

Works count: 1,659

Citation count: 59,200