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tram
Description:
TRAM is a Toll-like receptor adaptor molecule that mediates innate immune signaling, particularly downstream of Toll-like receptor 4.
Primary topic:
transportation and logistics systems (25%)
Related topics:
transportation and logistics systems (25%),
Transportation Planning and Optimization (13%)
OpenAlex ID:
keywords/tram
Toll-like receptors in innate immunity
2004
·
K. Takeda
·
International Immunology
·
3,328
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
2007
·
Luke A. J. O'Neill
, Andrew G. Bowie
·
Nature reviews. Immunology
·
2,675
TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
2020
·
Anna Ciesielska
, Marta Matyjek
, et al.
·
Cellular and Molecular Life Sciences
·
1,399
PDF
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
2008
·
Jonathan C Kagan
, Tian Su
, et al.
·
Nature Immunology
·
1,253
Signal transduction by the lipopolysaccharide receptor, Toll‐like receptor‐4
2004
·
Eva M. Pålsson‐McDermott
, Luke A. J. O'Neill
·
Immunology
·
1,252
LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
2003
·
Katherine A. Fitzgerald
, Daniel C. Rowe
, et al.
·
The Journal of Experimental Medicine
·
1,193
PDF
TRAM is specifically involved in the Toll-like receptor 4–mediated MyD88-independent signaling pathway
2003
·
Masahiro Yamamoto
, Shintaro Sato
, et al.
·
Nature Immunology
·
1,051
Recognition and Signaling by Toll-Like Receptors
2006
·
A. Phillip West
, Anna Alicia Koblansky
, et al.
·
Annual Review of Cell and Developmental Biology
·
721
Toll‐like receptors and adaptor molecules in liver disease
2008
·
Ekihiro Seki
, David A. Brenner
·
Hepatology
·
720
PDF
TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules
2010
·
Naoko Matsunaga
, Noboru Tsuchimori
, et al.
·
Molecular Pharmacology
·
594
The Toll–IL-1 receptor adaptor family grows to five members
2003
·
Luke A.J. O'Neill
, Katherine A Fitzgerald
, et al.
·
Trends in Immunology
·
492
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
2006
·
C.-J. Chen
·
Journal of Clinical Investigation
·
477
PDF
Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection
2015
·
Allison L. Totura
, Alan Whitmore
, et al.
·
mBio
·
455
TLR2 and TLR4 in Autoimmune Diseases: a Comprehensive Review
2013
·
Yu Liu
, Heng Yin
, et al.
·
Clinical Reviews in Allergy & Immunology
·
366
The immunobiology of the TLR9 subfamily
2004
·
Hermann Wagner
·
Trends in Immunology
·
341
Signalling adaptors used by Toll-like receptors: An update
2008
·
Elaine F. Kenny
, Luke A.J. O’Neill
·
Cytokine
·
332
Broad-Host-Range Expression Vectors with Tightly Regulated Promoters and Their Use To Examine the Influence of TraR and TraM Expression on Ti Plasmid Quorum Sensing
2008
·
Sharik R. Khan
, Jennifer Gaines
, et al.
·
Applied and Environmental Microbiology
·
331
The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction
2006
·
Daniel C. Rowe
, Anne F. McGettrick
, et al.
·
Proceedings of the National Academy of Sciences
·
286
Microbial recognition by Toll-like receptors
2003
·
Kiyoshi Takeda
, Shizuo Akira
·
Journal of Dermatological Science
·
284
Synthetic methodologies of achiral diarylmethanols, diaryl and triarylmethanes (TRAMs) and medicinal properties of diaryl and triarylmethanes-an overview
2014
·
Sankalan Mondal
, Gautam Panda
·
RSC Advances
·
280
PDF
Astragalus polysaccharides exerts immunomodulatory effects via TLR4-mediated MyD88-dependent signaling pathway in vitro and in vivo
2017
·
Lijing Zhou
, Zijing Liu
, et al.
·
Scientific Reports
·
271
PDF
Avian toll-like receptors
2010
·
Robert Brownlie
, Brenda Allan
·
Cell and Tissue Research
·
259
Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling
2008
·
Natsuko Tanimura
, Shinichiroh Saitoh
, et al.
·
Biochemical and Biophysical Research Communications
·
250
Intestinal barrier permeability: the influence of gut microbiota, nutrition, and exercise
2024
·
Tetiana R. Dmytriv
, Kenneth B. Storey
, et al.
·
Frontiers in Physiology
·
248
Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities
2010
·
Jiankun Zhu
, Chandra Mohan
·
Mediators of Inflammation
·
248
PDF
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Works count:
6,636
Citation count:
41,030
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