Keyword

transduction efficiency

Description: Transduction efficiency is the proportion of target cells successfully receiving genetic material from a viral vector in gene transfer or cell therapy.

Primary topic: Virus-based gene therapy research (71%)

OpenAlex ID: keywords/transduction-efficiency

Microscale Heat Transfer Transduced by Surface Plasmon Resonant Gold Nanoparticles

2007 · D. Keith Roper, W. Ahn, et al. · The Journal of Physical Chemistry C · 1,715

Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus

1998 · Xiao Xiao, Juan Li, et al. · Journal of Virology · 1,381

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Engineering adeno-associated virus vectors for gene therapy

2020 · Chengwen Li, R. Jude Samulski · Nature Reviews Genetics · 1,172

A peptide carrier for the delivery of biologically active proteins into mammalian cells

2001 · May C. Morris, Julien Depollier, et al. · Nature Biotechnology · 1,018

Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo

2002 · F Scherer, M Anton, et al. · Gene Therapy · 932

A small cosmid for efficient cloning of large DNA fragments

1980 · Barbara Hohn, John Collins · Gene · 817

Cross-Packaging of a Single Adeno-Associated Virus (AAV) Type 2 Vector Genome into Multiple AAV Serotypes Enables Transduction with Broad Specificity

2002 · Joseph E. Rabinowitz, Fabienne Rolling, et al. · Journal of Virology · 764

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Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

2001 · DM McCarty, PE Monahan, et al. · Gene Therapy · 736

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

2009 · Robert H Kutner, Xian-Yang Zhang, et al. · Nature Protocols · 670

Versatile retroviral vectors for potential use in gene therapy.

1994 · R G Hawley, F H Lieu, et al. · PubMed · 652

Gene Therapy for Cancer: What Have We Done and Where Are We Going?

1997 · J. A. Roth, R. J. Cristiano · JNCI Journal of the National Cancer Institute · 636

From the Cover: Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system

2000 · B. L. Davidson · Proceedings of the National Academy of Sciences · 597

Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses

2008 · Li Zhong, Baozheng Li, et al. · Proceedings of the National Academy of Sciences · 558

Highly efficient molecular delivery into mammalian cells using carbon nanotube spearing

2005 · Dong Cai, Jennifer M Mataraza, et al. · Nature Methods · 552

Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo

2003 · D M McCarty, H Fu, et al. · Gene Therapy · 548

Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis

1996 · K J Fisher, G P Gao, et al. · Journal of Virology · 547

Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system

2000 · Beverly L. Davidson, Colleen S. Stein, et al. · Proceedings of the National Academy of Sciences · 531

Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain

2013 · Dominik F. Aschauer, Sebastian Kreuz, et al. · PLoS ONE · 522

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Self-complementary AAV Vectors; Advances and Applications

2008 · Douglas M McCarty · Molecular Therapy · 516

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High-Level Transduction and Gene Expression in Hematopoietic Repopulating Cells Using a Human Imunodeficiency Virus Type 1-Based Lentiviral Vector Containing an Internal Spleen Focus Forming Virus Promoter

2002 · Christophe Demaison, Kathryn Parsley, et al. · Human Gene Therapy · 486

Viral Vectors for Gene Therapy: Translational and Clinical Outlook

2015 · Melissa A. Kotterman, Thomas W. Chalberg, et al. · Annual Review of Biomedical Engineering · 445

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Packaging Capacity of Adeno-Associated Virus Serotypes: Impact of Larger Genomes on Infectivity and Postentry Steps

2005 · Joshua C. Grieger, Richard J. Samulski · Journal of Virology · 419

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Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo

2003 · Z Wang, H-I Ma, et al. · Gene Therapy · 413

Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors

2003 · Oliver J Müller, Felix Kaul, et al. · Nature Biotechnology · 412

Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus

1997 · John G. Flannery, Sergei Zolotukhin, et al. · Proceedings of the National Academy of Sciences · 407

Works count: 3,950

Citation count: 101,800