Get started
Keyword

TRIF

Description: An intracellular adaptor protein, encoded by TICAM1, that mediates signaling by Toll-like receptors and promotes inflammatory and interferon responses.
Wikidata ID: wiki/Q4050587
OpenAlex ID: keywords/trif
Toll-like receptors in innate immunity
2004 · K. Takeda · International Immunology · 3,328
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
2003 · Masahiro Yamamoto, Shintaro Sato, et al. · Science · 3,238
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
2007 · Luke A. J. O'Neill, Andrew G. Bowie · Nature reviews. Immunology · 2,675
TLR signaling pathways
2004 · Kiyoshi Takeda, Shizuo Akira · Seminars in Immunology · 2,466
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
2015 · Siqi Liu, Xin Cai, et al. · Science · 1,918
MicroRNA-155 is induced during the macrophage inflammatory response
2007 · Ryan M. O'Connell, Konstantin D. Taganov, et al. · Proceedings of the National Academy of Sciences · 1,866
VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling
2005 · Liang-Guo Xu, Yan-Yi Wang, et al. · Molecular Cell · 1,853
PDF
Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury
2008 · Yumiko Imai, Keiji Kuba, et al. · Cell · 1,356
PDF
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
2008 · Jonathan C Kagan, Tian Su, et al. · Nature Immunology · 1,253
Signal transduction by the lipopolysaccharide receptor, Toll‐like receptor‐4
2004 · Eva M. Pålsson‐McDermott, Luke A. J. O'Neill · Immunology · 1,252
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 · K. Hoebe, X. Du, et al. · Nature · 1,231
Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling
2002 · Masahiro Yamamoto, Shintaro Sato, et al. · The Journal of Immunology · 1,227
PDF
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
2018 · Zhenyu Zhong, Shuang Liang, et al. · Nature · 1,199
LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
2003 · Katherine A. Fitzgerald, Daniel C. Rowe, et al. · The Journal of Experimental Medicine · 1,193
PDF
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF
2005 · Kui Li, Eileen Foy, et al. · Proceedings of the National Academy of Sciences · 1,092
TRAM is specifically involved in the Toll-like receptor 4–mediated MyD88-independent signaling pathway
2003 · Masahiro Yamamoto, Shintaro Sato, et al. · Nature Immunology · 1,051
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
2005 · Hans Häcker, Vanessa Redecke, et al. · Nature · 968
PDF
Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling
2015 · Robert Caesar, Valentina Tremaroli, et al. · Cell Metabolism · 958
PDF
Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL
2013 · William J. Kaiser, Haripriya Sridharan, et al. · Journal of Biological Chemistry · 954
PDF
Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children
2016 · Michelle M. Stein, Cara L. Hrusch, et al. · New England Journal of Medicine · 935
PDF
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
2008 · Mark E. Kleinman, Kiyoshi Yamada, et al. · Nature · 929
PDF
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
2005 · Gagik Oganesyan, Supriya K. Saha, et al. · Nature · 881
Toll-like Receptor 4 Is a Sensor for Autophagy Associated with Innate Immunity
2007 · Yi Xu, Chinnaswamy Jagannath, et al. · Immunity · 879
PDF
RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation
2004 · Etienne Meylan, Kim Burns, et al. · Nature Immunology · 850
PDF
Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
2011 · James Harris, Michelle Hartman, et al. · Journal of Biological Chemistry · 793
Works count: 2,388
Citation count: 138,000
Year
Topic
Type